Health Highlights: April 22, 2019

Here are some of the latest health and medical news developments, compiled by the editors of HealthDay: FDA Approves First Device to Treat Children With ADHD The first medical device to treat children with attention-deficit/hyperactivity disorder...
Source: - Daily MedNews - Category: General Medicine Source Type: news

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Nature, Published online: 24 June 2019; doi:10.1038/d41586-019-01949-2A molecular dialogue between neurons and star-shaped cells called astrocytes in the striatum of the mouse brain leads to behavioural hyperactivity and inattentiveness that are reminiscent of attention-deficit hyperactivity disorder.
Source: Nature AOP - Category: Research Authors: Source Type: research
ConclusionsOur results suggest a causal role of insomnia in autism spectrum disorder and bipolar disorder. Future disease models should include insomnia as a factor for these two disorders to develop effective interventions. More detailed mechanism studies may also be inspired by this causal inference.
Source: European Psychiatry - Category: Psychiatry Source Type: research
Abnormal functional brain asymmetry and deficient response inhibition are two core symptoms of attention deficit hyperactivity disorder (ADHD). However, it is not known whether these symptoms are inter-related and whether they result from altered frontal excitability or compromised interhemispheric connectivity. We studied these issues in 52 ADHD and 43 non-clinical adults by comparing: (1) stop-signal reaction time (SSRT); (2) frontal asymmetry of the N200 event-related potential component, which is evoked during response inhibition and is lateralized to the right hemisphere; (3) TMS-evoked potential (TEP) in the right fr...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - Category: Neurology Authors: Source Type: research
Publication date: Available online 22 June 2019Source: Seminars in Cell &Developmental BiologyAuthor(s): Maude Bordeleau, Micaël Carrier, Giamal N. Luheshi, Marie-Ève TremblayAbstractIn addition to their traditional role as immune sentinels, recent discoveries over the last decade have shown that microglial functions now include regulation of neuronal/glial cell migration, differentiation and maturation, as well as neuronal network formation. It was thus proposed that disruption of these microglial roles, during critical periods of brain development, could lead to the pathological onset of several neurodeve...
Source: Seminars in Cell and Developmental Biology - Category: Cytology Source Type: research
We examined whether SCT and processing speed predict different functional correlates within children and adolescents with ADHD. Participants were 193 clinically-referred youth meeting DSM ADHD criteria without comorbid conditions (mean age = 9.9 years, SD = 2.5; age range 6-16). The incremental utility of SCT and processing speed to predict (1) adaptive functioning and (2) academic achievement, after controlling for age, sex, medication status, and ADHD symptom burden, was assessed using hierarchical multiple regressions. SCT symptoms significantly predicted adaptive functioning, accounting...
Source: Child Psychiatry and Human Development - Category: Child Development Authors: Tags: Child Psychiatry Hum Dev Source Type: research
AbstractObjectiveSleep problems are common in adults with attention-deficit/hyperactivity disorder (ADHD). The presence of sleep problems at the time of presentation for ADHD treatment could impact the level of improvement in ADHD symptoms or executive function occurring with ADHD pharmacotherapy. Therefore, we examined the influence of baseline sleep quality on the effects of SHP465 mixed amphetamine salts (MAS) extended-release.MethodsAdults (18 –55 years) withDiagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision-defined ADHD and baseline ADHD Rating Scale IV (ADHD-RS-IV) total s...
Source: CNS Drugs - Category: Neurology Source Type: research
CONCLUSIONS: The review suggests that there is little evidence to support or refute social skills training for children and adolescents with ADHD. We may need more trials that are at low risk of bias and a sufficient number of participants to determine the efficacy of social skills training versus no training for ADHD. The evidence base regarding adolescents is especially weak. PMID: 31222721 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Tags: Cochrane Database Syst Rev Source Type: research
The original version of this article unfortunately contained a mistake. The captions of Figures  1 and 2 were swapped.
Source: ADHD Attention Deficit and Hyperactivity Disorders - Category: Psychiatry Source Type: research
Publication date: Available online 19 June 2019Source: Developmental Cognitive NeuroscienceAuthor(s): C. Nikki Arrington, Jeffrey G. Malins, Rebecca Winter, W. Einar Mencl, Kenneth R. Pugh, Robin MorrisAbstractThe aim of the current study was to develop an fMRI task capable of characterizing individual differences in reading and attentional domains. Forty-nine students with a range of reading and attentional control abilities completed an event-related fMRI oddball task consisting of printed word and false font stimuli. Reading network activation was assessed by contrasting printed words with false font stimuli. Left infer...
Source: Developmental Cognitive Neuroscience - Category: Neuroscience Source Type: research
People living with autism are sensitive to the social world and the environment in general. They could experience great difficulties in social situations, have anxieties, fears, phobias, or sensory sensitivities. On the other hand, they could be on good terms with technologies: social stories apps can navigate them in difficult situations, virtual and augmented reality can offer a safe space for them to exercise, and artificial intelligence helps in early detection. We scoured the ground carefully and hereby present you the intersections of autism and digital health. Raymond Babbitt’s heritage and the chronicles ...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Future of Medicine AI app AR artificial intelligence autism digital digital health digital technology games genetics health app health apps Innovation virtual reality VR Source Type: blogs
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