Molecules, Vol. 24, Pages 1576: An Investigation on Glucuronidation Metabolite Identification, Isozyme Contribution, and Species Differences of GL-V9 In Vitro and In Vivo

In conclusion, 5-O-glucuronide GL-V9 is the dominant phase II metabolite of GL-V9 in vivo and in vitro, whose formation rate and efficiency are closely related to isoform-specific metabolism profiles and the distribution of UGTs in different tissues of different species.

Source: Molecules - April 21, 2019 Category: Chemistry Authors: Han Xing Dexuan Kong Chen Ning Ying Kong Chang Ren Yujie Cheng Hui Cai Jubo Wang Di Zhao Ning Li Xijing Chen Zhiyu Li Yang Lu Tags: Article Source Type: research