A Clinical Applicable Gene Expression Classifier Reveals Intrinsic and Extrinsic Contributions to Consensus Molecular Subtypes in Primary and Metastatic Colon Cancer.

CONCLUSION: We describe the utility of a Nanostring panel for CMS classification of FFPE clinical samples. Our work reveals the impact of intrinsic and extrinsic factors on CRC heterogeneity during disease progression.
PMID: 31004000 [PubMed - as supplied by publisher]

Source: Clinical Cancer Research - April 18, 2019 Category: Cancer & Oncology Authors: Piskol R, Huw LY, Sergin I, Kim D, Kljavin NM, Tam R, Patel R, Burton J, Penuel E, Qu X, Koeppen H, Sumiyoshi T, de Sauvage FJ, Lackner MR, de Sousa E Melo F, Kabbarah O, Klijn C, Modrusan Z Tags: Clin Cancer Res Source Type: research