A constitutional activating MET mutation makes the genetic link between malignancies and chronic inflammatory diseases.

CONCLUSIONS: Our study opens a considerable field of application in the domain of constitutional genetics, to establish genetic links between cancers and other very different severe diseases.
PMID: 31004003 [PubMed - as supplied by publisher]

Source: Clinical Cancer Research - April 18, 2019 Category: Cancer & Oncology Authors: Morad EB, Do Cruzeiro M, Leboeuf C, Loisel-Ferreira I, Fédronie C, Ferreira C, Ait El Far R, Ziol M, Espié M, Falgarone G, Cassinat B, Kiladjian JJ, Feugeas JP, Janin A, Bousquet G Tags: Clin Cancer Res Source Type: research