Association of opioid receptor gene polymorphisms with drinking severity and impulsivity related to alcohol use disorder in a Korean population.

CONCLUSION: Genetic variations in opioid receptors may contribute to symptom severity and impulsivity in AUD patients. PMID: 31004399 [PubMed - as supplied by publisher]
Source: CNS Neuroscience and Therapeutics - Category: Neuroscience Authors: Tags: CNS Neurosci Ther Source Type: research

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ConclusionsThe high treatment gap in the population is concerning and highlights the need to promote help-seeking and uptake of treatment. Given the unique demographic characteristics, i.e., those with higher education and employed were more likely not to seek treatment, targeted interventions in the educational and workplace settings should be implemented.
Source: Social Psychiatry and Psychiatric Epidemiology - Category: Psychiatry Source Type: research
We were very pleased to read the excellent article by Swets et al. [1], who examined longitudinally for 3 years motor (akathisia, dyskinesia, parkinsonism and dystonia) and obsessive compulsive symptoms (OCS) in psychotic patients and individuals with i...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
Publication date: Available online 18 June 2019Source: Neuroscience &Biobehavioral ReviewsAuthor(s): Rita Pasion, Fernando BarbosaAbstractThe comorbidity between discrete clinical diagnosis occurs in higher levels than prevalence rates, indicating that mental disorders are systematically overcategorized. Dimensional models – as the Internalizing-Externalizing Spectrum – claim for a common latent structure of psychopathology. The current meta-analysis aims to evaluate whether the externalizing and internalizing latent factors of the psychopathological spectrum display common and distinctive neurobiological s...
Source: Neuroscience and Biobehavioral Reviews - Category: Neuroscience Source Type: research
CONCLUSION: Similar to the past SCID versions, kappa values were found to be quite high and all were statistically significant. The Turkish version of SCID-5/ CV can be reliably used in both clinical practice and clinical studies. PMID: 31170307 [PubMed - in process]
Source: Turkish Journal of Psychiatry - Category: Psychiatry Authors: Tags: Turk Psikiyatri Derg Source Type: research
What Are 5 Underlying Reasons for Addiction? Addiction always stems from a root cause, also known as one of the reasons for addiction. It is extremely important to treat both the root cause of the addiction in addition to the physical addiction itself. Staying sober involves much more than just detoxing from drugs or alcohol and abstaining from them in the future. It also involves finding the underlying reasons for the addiction and treating that as well, so that it does not exacerbate the addiction in the future. This is why so many people fail when they attempt to quit using drugs or alcohol cold turkey. While there can ...
Source: Cliffside Malibu - Category: Addiction Authors: Tags: Abuse Addiction Addiction Recovery Addiction to Pharmaceuticals Addiction Treatment and Program Resources Alcohol Alcoholism Anxiety Children Depression Depression Treatment Drug Treatment LGBT LGBTQ Mental Health Painkiller Source Type: blogs
Obsessive-compulsive disorder (OCD) and substance-use disorders (SUDs) co-occur at high rates, which is related to poorer psychosocial outcomes. Prior work suggests that, among veterans in the Veterans Health Administration (VHA), OCD is underdiagnosed ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
Abstract Orthorexia nervosa (ON) is a condition described as a pathological obsession with healthy eating. This paper will review the prevalence of ON and how ON is measured. The primary objective is to critically analyze findings on the psychosocial risk factors associated with ON, to consider its relation to other mental disorders, and to offer directions for future research. The key words "orthorexia" and "orthorexia nervosa" were searched in the databases PsycINFO and MEDLINE/PubMed. This paper reviewed peer-reviewed articles published up until December 31st, 2018. Quality assessment was co...
Source: Appetite - Category: Nutrition Authors: Tags: Appetite Source Type: research
Hui Xu1,2,3, Chenguang Guo1, Haining Li1, Lin Gao2, Ming Zhang1* and Yuan Wang1* 1Department of Medical Imaging, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China 2Key Laboratory of Biomedical Information Engineering of Education Ministry, Institute of Biomedical Engineering, Xi'an Jiaotong University, Xi'an, China 3Faculty of Dentistry, University of Toronto, Toronto, ON, Canada Background and Purpose: Hemifacial spasm (HFS) is a rare neuromuscular disorder characterized by unilateral, involuntary, and paroxysmal contractions of orofacial muscles. To eluci...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
In conclusion, our study demonstrates that TS patients manifest “trait” abnormalities in the timing of sequential motor tasks, which are in keeping with the continuation phase of time processing, likely controlled by the sensorimotor loop of the cortico-basal ganglia network. We also show that the abnormal lateralization of fine motor control, previously reported in the context of the structural sequencing of fine motor tasks, extends also to motor timing accuracy. Finally, we highlight SMA connectivity as a potentially pivotal neural substrate of adaptive compensation of motor timing deficits in fine manual ta...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Conclusion: Some patients with psychiatric syndromes and increased ANA titers may suffer from psychiatric variants of SLE, even if the American College of Rheumatology criteria for SLE are not met. Whether the psychiatric symptoms in our patient represent a prodromal stage with the later manifestation of full-blown SLE or a subtype of SLE with isolated CNS involvement remains unclear. Regardless, early diagnosis and initiation of immunosuppressive treatment are essential steps in preventing further disease progression and organ damage. Intrathecal ANAs with extractable nuclear antigen differentiation may be a more sensitiv...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
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