CXCR4 signaling at the ovine fetal-maternal interface regulates vascularization, CD34 + cell presence, and autophagy in the endometrium.

This study suggests that CXCL12-CXCR4 signaling governs placental homeostasis by serving as a critical upstream mediator of vascularization and cell viability, thereby ensuring appropriate placental development. PMID: 31004477 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31004477?dopt=Abstract

Source: Biology of Reproduction - April 19, 2019 Category: Reproduction Medicine Authors: Runyan CL, McIntosh SZ, Maestas MM, Quinn KE, Boren BP, Ashley RL Tags: Biol Reprod Source Type: research

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