Evaluation of Propofol in Comparison with Other General Anesthetics for Surgery in Children Younger than 3 Years: a Systematic Review and Meta-Analysis.

CONCLUSION: This systematic review and meta-analysis indicates that propofol use for general anesthesia in young healthy children undergoing surgery does not increase complications and that propofol could be at least comparable to other anesthetic agents. PMID: 31001938 [PubMed - in process]
Source: Journal of Korean Medical Science - Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

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CONCLUSIONS: Noncardiac surgery was associated with an increase in atherogenic leukocyte subsets. In a post hoc analysis, elevated pre-OP presepsin was associated with MACCE and improved NT-proBNP-based risk assessment. After validation in an independent data set, a presepsin cutoff of 184 pg·mL might qualify to complement NT-proBNP-based risk prediction, thereby increasing the proportion of correctly identified high-risk patients. PMID: 31094810 [PubMed - in process]
Source: Anesthesia and Analgesia - Category: Anesthesiology Authors: Tags: Anesth Analg Source Type: research
PATENT FORAMEN OVALE (PFO) is the most common congenital defect of the atrial septum, with reported incidences ranging between 27% and 34% in autopsy studies.1 During embryonic life, the PFO is a physiological discontinuity of the septum secundum that allows the oxygenated placental blood to bypass the non-functional lungs of the fetus. There are 2 overlapping components of the developing atrial septum. On the right, the septum secundum stems from an infolding of the atrial walls and contains a posteroinferior oval-shaped opening, the foramen ovale.
Source: Journal of Cardiothoracic and Vascular Anesthesia - Category: Anesthesiology Authors: Tags: Expert Review Source Type: research
Conditions:   Coronary Heart Disease;   Anemia;   Bronchial Asthma;   Stroke;   Epilepsy;   Parkinson's Disease;   Heart Rhythm Disorders;   Alzheimer's Disease;   Neuromuscular Diseases;   Diabetes;   Chronic Heart Failure;   Chronic Obstructive Pulmonary Disease;   Chronic Kidney  Diseases Intervention:   Sponsors:   Russian Federation of Anesthesiologists and Reanimatologists;   Kuban State Medical University Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
The impact of anesthesia strategy on the outcomes of acute ischemic stroke (AIS) patients undergoing endovascular treatment is currently controversy. Thus, we performed this meta-analysis to compare the differ...
Source: BMC Anesthesiology - Category: Anesthesiology Authors: Tags: Research article Source Type: research
ConclusionAdministration of ESA and iron therapy reduced the risk for RBC transfusion compared with iron therapy alone in patients undergoing cardiac and non-cardiac surgery. Nevertheless, publication bias and heterogeneity reduces the confidence of the finding. Although the analysis was probably under-powered for some outcomes, no difference in the incidence of serious adverse events was observed with ESA and iron compared with iron alone. Further large prospective trials are required to confirm these findings.
Source: Canadian Journal of Anesthesia - Category: Anesthesiology Source Type: research
Background: Many asphyxiated neonates have cardiac complications including arrhythmia and contractile dysfunction. Little is known about the relationship between heart rate (HR) and diastolic function in asphyxiated neonates. We studied the relationship between HR and left ventricular isovolumic relaxation in neonatal asphyxia. Methods: Term newborn piglets were anesthetized and acutely instrumented with the placement of Millar catheter in the left ventricle. Hemodynamic parameters including HR, cardiac output, stroke volume, dP/dtmax and dP/dtmin, and isovolumic relaxation time constant (Tau) were continuously measured...
Source: Frontiers in Physiology - Category: Physiology Source Type: research
To identify the predictors of in-hospital mortality in patients who develop perioperative acute ischemic stroke (PAIS) associated with noncardiac, nonvascular, and non-neurologic surgery.
Source: Journal of Cardiothoracic and Vascular Anesthesia - Category: Anesthesiology Authors: Tags: Original Article Source Type: research
Despite large randomized controlled trials demonstrating similar outcomes for of-pump or on-pump coronary artery bypass grafting, the debate between proponents of each technique remains current.1 On-pump technique improves surgical exposure on a nonbeating heart but exposes the patient to a powerful inflammatory response and to ischemic stroke owing to cross clamping and cannulation. Off-pump coronary artery bypass (OPCAB) may reduce blood transfusion, postoperative length of hospital stay, postoperative neurocognitive decline, and systemic anticoagulation, but heart repositioning may be associated with hemodynamic instabi...
Source: Journal of Cardiothoracic and Vascular Anesthesia - Category: Anesthesiology Authors: Tags: Letter to the Editor Source Type: research
AbstractAssessment of right ventricular (RV) function is crucial since RV failure with a reduced cardiac output (CO) is associated with compromised outcome in cardiac surgery. Echocardiographic evaluation of RV function is commonly used, but a reduction in tricuspid annular plane systolic excursion (TAPSE) and tricuspid annulus tissue Doppler imaging (S ′) have been observed independently of clinical signs of RV failure. This has led to uncertainty of these variables’ validity in cardiac surgery. To describe transesophageal echocardiographic (TEE) measures of RV function during coronary artery bypass graft surg...
Source: The International Journal of Cardiovascular Imaging - Category: Radiology Source Type: research
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