Is maternal dietary selenium intake related to antioxidant status and the occurrence of pregnancy complications?

Publication date: Available online 19 April 2019Source: Journal of Trace Elements in Medicine and BiologyAuthor(s): Pieczyńska Joanna, Płaczkowska Sylwia, Sozański Rafał, Orywal Karolina, Mroczko Barbara, Grajeta HalinaAbstractSelenium (Se) is a trace element essential for the appropriate course of vital processes in the human body. It is also a constituent of the active center of glutathione peroxidase and other antioxidant compounds which play an important role in red-ox processes. Associations between lower blood selenium concentration and obstetric complications has been reported in many studies. The aim of this study was to determine the dietary selenium intake and serum selenium content in pregnant Polish women and relate this to antioxidant status as whole blood glutathione peroxidase (GPX) activity, serum uric acid (UA) content and serum total antioxidant status (TAS) and pregnancy complications occurrence. Ninety-four pregnant women at a mean age 30.6 ± 5.4 years from the Lower Silesia region of Poland were recruited to the study, 37% of studied group had pregnancy complications. The mean reported Se intake and serum selenium content for Polish pregnant women was in the first trimester – 53.99 µg/day and 44.36 µg/l, the second trimester – 58.93 µg/day and 43.16 µg/l and the third trimester – 62.89 µg/day and 40.97 µg/l, respectively. Selenium intak...
Source: Journal of Trace Elements in Medicine and Biology - Category: Biochemistry Source Type: research

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ConclusionOur results suggested HBV infection did not appear to be detrimental to the outcome of IVF/ICSI treatment.
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
CONCLUSION The available evidence, limited to low evidence level case reports and series, indicates cutaneous laser treatment during pregnancy is safe for both mother and fetus. Furthermore, laser physics and optics dictate there should theoretically be no risk of fetal laser exposure from commonly used cutaneous lasers.
Source: Dermatologic Surgery - Category: Dermatology Tags: Review Article Source Type: research
In conclusion, prenatal and recent MeHg exposure had no consistent pattern of associations to support the hypothesis that they are adversely associated with heart rate variability in this study population that consumes large amounts of fish.
Source: Neurotoxicology and Teratology - Category: Toxicology Source Type: research
CONCLUSIONS: Benzodiazepine monotherapy is utilized in nearly 1 in 10 patients treated for depression. Adults aged 45 to 65 years, patients prescribed opioids, patients seen by primary care providers, and those with underlying anxiety, epilepsy, or pulmonary disorders are at highest risk. PMID: 31120203 [PubMed - in process]
Source: Journal of Clinical Psychiatry - Category: Psychiatry Tags: J Clin Psychiatry Source Type: research
ConclusionsHuman IGF-1 gene may be a candidate gene for GDM and T2DM risk, as our study suggests a significant association between the IGF-I rs35767 and rs5742612 polymorphisms and the risk of T2DM and GDM in pregnant women, whereas there was no association for rs2288377.
Source: Meta Gene - Category: Genetics & Stem Cells Source Type: research
Publication date: Available online 24 May 2019Source: Best Practice &Research Clinical Obstetrics &GynaecologyAuthor(s): Maria Emilia SolanoAbstractDuring human pregnancy, trophoblast cells, the main cellular component of the placenta invades deeply into uterine blood vessels and the modified endometrium (decidua). Hence, the maternal immune system must adapt: successful pregnancy requires the tolerance of genetically different (allogenic) cells while the mother’s immune competence is maintained. This tolerance is ensured through multiple overlapping and occasionally redundant innate and adaptive immune mecha...
Source: Best Practice and Research Clinical Obstetrics and Gynaecology - Category: OBGYN Source Type: research
Authors: Paladini D, Donarini G, Conti A, Constanza De Angelis L, Witte MH, Genesio R, Bernas M, Bellini T, Boccardo F, Ramenghi LA, Bellini C Abstract The aim of this study is to assess whether early cervical lymphatic obstruction is associated with a sonographically detectable dilatation of the ventricular system in the 1st trimester of pregnancy. In particular, the objective is to assess whether fetuses with non-immune hydrops fetalis (NIHF), cystic hygroma, or enlarged nuchal translucency (NT) have a greater atrial width/biparietal diameter (AW/BPD) ratio than normal at time of the combined first trimester scre...
Source: Lymphology - Category: Internal Medicine Tags: Lymphology Source Type: research
The U.S. diagnostic market celebrated three regulatory firsts last week.  1. FDA Authorizes Marketing of First Zika Test Until now, tests for detecting Zika virus immunoglobulin (IgM) antibodies in blood were only authorized for emergency use under FDA's Emergency Use Authorization (EUA) authority. On Thursday, the agency said it has authorized marketing of the ZIKV Detect 2.0 IgM Capture ELISA under the agency's traditional premarket authority. The test is manufactured by InBios International. “At the onset of the Zika virus outbreak, when little was known about the disease or how...
Source: MDDI - Category: Medical Devices Authors: Tags: Regulatory and Compliance IVD Source Type: news
The number of infants born with HIV in the United States has decreased for years, approaching the Centers for Disease Control and Prevention’s incidence goal for eliminating perinatal HIV transmission. We reviewed recent literature on perinatal HIV transmission in the United States. Among perinatally HIV-exposed infants (whose mothers have HIV, without regard to infants’ HIV diagnosis), prenatal and natal antiretroviral use has increased, maternal HIV infection is more frequently diagnosed before pregnancy and breast-feeding is uncommon. In contrast, mothers of infants with HIV are tested at a lower rate for HI...
Source: The Pediatric Infectious Disease Journal - Category: Infectious Diseases Tags: HIV Reports Source Type: research
Conclusion: Misconceptions exist regarding safety/efficacy of antenatal vaccination, and framing information towards the child’s safety may increase uptake. Education of HCPs is essential, and vaccine promotion should be incorporated into routine antenatal care, with an emphasis on women from ethnic minorities. Administration of vaccines in primary care presents logistical barriers; however, support for alternative sites appears low among HCPs.
Source: The Pediatric Infectious Disease Journal - Category: Infectious Diseases Tags: Maternal-Neonatal Reports Source Type: research
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