Biological monitoring of o-toluidine in urine pretreated by an enzymatic deconjugation method.

CONCLUSIONS: OT and its six metabolites can each be determined with LC-MS. The alkaline method is not so optimal for exact biological monitoring. Rather, the sum of urinary OT, NHM, and ACR measured by the enzymatic method is a better index, and "end of the workweek" is a good urine-sampling time for the biological monitoring of OT exposure. PMID: 31002462 [PubMed - as supplied by publisher]
Source: Journal of Occupational Health - Category: Occupational Health Tags: J Occup Health Source Type: research