GSE68092 Gene expression profiling of B-cell and non-B-cell fractions of follicular lymphoma

Contributors : Min Zhang ; Jason Westin ; Zhiqiang Wang ; Larry W Kwak ; Sattva S Neelapu ; Wencai Ma ; R E DavisSeries Type : Expression profiling by arrayOrganism : Homo sapiensExcisional biopsies of lymph nodes involved by follicular lymphoma (FL) were obtained from previously-untreated, advanced-stage patients to generate heterohybridomas and idiotype vaccine for a clinical trial (PMID: 21632504). Residual, viably-cryopreserved suspensions of disaggregated cells were magnetically sorted by negative selection into nominal B (CD3-depleted) and non-B (NB; CD19- and CD20-depleted) fractions. Total RNA was extracted from each fraction for separate gene expression profiling (GEP). Technically-satisfactory GEP results were obtained from both fractions for 43 patients.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by array Homo sapiens Source Type: research