Insular Brain Tumor Surgery: Part 3—Intraoperative Technology

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Source: Contemporary Neurosurgery - Category: Neurosurgery Tags: ARTICLE Source Type: research

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Publication date: Available online 23 May 2019Source: Journal of Thermal BiologyAuthor(s): Amir Abdolhosseinzadeh, Afsaneh Mojra, Ali AshrafizadehAbstractFocused ultrasound surgery (FUS) is a non-invasive thermal therapeutic method which has been emerged in the field of brain tumors treatment. During intraoperative brain surgery, application of FUS can significantly increase the accuracy of thermal ablation of tumor while reducing undesirable damage to healthy brain tissue. The main objective of this study is acquiring acoustic transducer specifications to achieve optimum thermal treatment in the tumoral tissue. 2D and 3D ...
Source: Journal of Thermal Biology - Category: Biology Source Type: research
J érôme Barriere was inadvertently missing in the original version of this article. He has participated to the study design, protocol writing and inclusion of a significant number of patients.
Source: European Journal of Nuclear Medicine and Molecular Imaging - Category: Nuclear Medicine Source Type: research
(Luxembourg Institute of Health) Until now, researchers have assumed that the growth of solid tumors originates from cancer stem cells characterized by specific surface markers, which develop in a fixed, hierarchical order. In a joint interdisciplinary project led by the Luxembourg Institute of Health (LIH), researchers now show that cancer cells of glioblastomas -- conspicuously aggressive solid brain tumors -- manifest developmental plasticity and their phenotypic characteristics are less constrained than believed.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news
In conclusion, our data have demonstrated that tMSCs secreted miR155-enriched exosomes, and the exosome incorporation and miR155 delivery further promoted migration in ATRT cells via a SMARCA4-dependent mechanism.
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Article Source Type: research
miR‑767‑5p inhibits glioma proliferation and metastasis by targeting SUZ12. Oncol Rep. 2019 May 13;: Authors: Zhang J, Xu S, Xu J, Li Y, Zhang J, Zhang J, Lu X Abstract A growing body of evidence implicates aberrant expression of microRNAs (miRNAs) and dysregulation of mRNA translation in the development and growth of cancer cells. However, little is known about the mechanisms of action of miRNAs in glioma, the most common form of adult‑onset malignant brain tumor. In the present study, the expression and function of miR‑767‑5p were examined in human glioblastoma multiforme (GBM) tissue speci...
Source: Oncology Reports - Category: Cancer & Oncology Tags: Oncol Rep Source Type: research
Authors: Kaley T, Nabors LB Abstract Meningiomas represent a full spectrum of tumors that are the most common type of brain tumor in adults. Although most are benign, recent research has shown that the recurrence rate is high, especially for WHO grades 2 and 3, and overall survival is poor for these grades. Treatment is evolving, and recently sunitinib and bevacizumab have shown promise compared with historical treatments. However, more research is needed to identify better treatments for meningiomas. Treatment of brain metastases is another evolving field. Studies suggest that stereotactic radiosurgery is preferab...
Source: Journal of the National Comprehensive Cancer Network : JNCCN - Category: Cancer & Oncology Tags: J Natl Compr Canc Netw Source Type: research
Publication date: Available online 23 May 2019Source: Seminars in Cancer BiologyAuthor(s): Galina Gabriely, Francisco J. QuintanaAbstractGlioblastoma (GBM) is an aggressive and incurable brain tumor; its malignancy has been associated with the activity of tumor infiltrating myeloid cells. Myeloid cells play important roles in the tumor control by the immune response, but also in tumor progression. Indeed, GBM exploits multiple mechanisms to recruit and modulate myeloid cells. The Aryl Hydrocarbon Receptor (AHR) is a ligand activated transcription factor implicated in the regulation of myeloid cells. In this review, we will...
Source: Seminars in Cancer Biology - Category: Cancer & Oncology Source Type: research
Publication date: Available online 23 May 2019Source: Biocybernetics and Biomedical EngineeringAuthor(s): Saravanan Alagarsamy, Kartheeban Kamatchi, Vishnuvarthanan Govindaraj, Yu-Dong Zhang, Arunprasath ThiyagarajanAbstractSegregation of tumor region in brain MR image is a prominent task that instantly provides easier tumor diagnosis, which leads to effective radiotherapy planning. For decades together, several segmentation methods for a brain tumor have been presented and until now, enhanced tumor segmentation procedure tends to be a challenging task because, MR images are mostly inbred with varied tumor dimensions of di...
Source: Biocybernetics and Biomedical Engineering - Category: Biomedical Engineering Source Type: research
ConclusionsThis study shows good long-term seizure outcomes after hemispherectomy. Seizure freedom has been achieved in the majority of the patients after 3 and 5 years.
Source: Interdisciplinary Neurosurgery - Category: Neurosurgery Source Type: research
Glioblastoma (GBM) is a fatal brain tumor, lacking effective treatment. Epidermal growth factor receptor (EGFR) is recognized as an attractive target for GBM treatment. However, GBMs have very poor responses t...
Source: Journal of Experimental and Clinical Cancer Research - Category: Cancer & Oncology Authors: Tags: Research Source Type: research
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