When psychiatric medications are abruptly discontinued, withdrawal symptoms may be mistaken for relapse

Withdrawal symptoms following the practice of discontinuation, or abruptly “coming off,” of psychiatric drugs in randomized clinical trials may be mistaken for relapse and bolster the case for continued use of medication, according to two new studies by UCLA researchers published in the journal Psychotherapy and Psychosomatics.Principal investigatorDavid Cohen, professor of social welfare in the UCLA Luskin School of Public Affairs, said that clinical trials employing a drug discontinuation procedure had not previously been studied systematically.“For years, observers have asked whether people getting more symptoms when they came off their medication was their disorder returning or the withdrawal effects from drugs that could be reduced by more gradual, patient-centered discontinuation,” Cohen said.In light of the difficulties that people have in discontinuing psychiatric medications, Cohen sought to answer that question, joined by co-author Alexander R écalt, a doctoral student in social welfare at UCLA Luskin who is also pursuing a master’s degree at the UCLA Fielding School of Public Health.They looked at how and why antidepressants, antipsychotics and stimulants were deliberately discontinued from trial subjects in more than 80 randomized controlled trials from 2000 –2017. The study also included benzodiazepines, a class of drugs such as Valium, upon which long-term users may become dependent and experience withdrawal symptoms.In...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news

Related Links:

AbstractPrevious research has demonstrated that sleep disturbances show little improvement with evidence ‐based psychotherapy for posttraumatic stress disorder (PTSD); however, sleep improvements are associated with PTSD treatment outcomes. The goal of the current study was to evaluate changes in self‐reported insomnia symptoms and the association between insomnia symptoms and treatment outcome dur ing a 3‐week intensive treatment program (ITP) for veterans with PTSD that integrated cognitive processing therapy (CPT), mindfulness, yoga, and other ancillary services. As part of standard clinical procedures, veterans (...
Source: Journal of Traumatic Stress - Category: Psychiatry & Psychology Authors: Tags: Research Article Source Type: research
ConclusionThis study provides evidence that metacognitive training is related to the modulation of DMN homogeneity in schizophrenia.
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Jeffrey A. SingerOn March 24 Arizona Governor Doug Ducey issuedanexecutive order allowing CRNA ’s (Certified Registered Nurse Anesthetists) to practice independently of physicians or surgeons, thus adding needed personnel to the health care work force during this public health emergency. Guidelines issued by the Centers for Medicare and Medicaid Services state that nurse anesthetists should be “supervised” by a physician, thus preventing these well ‐​trained specialized nurses from providing anesthesia independently while freeing up physician anesthesiologists so more patients can receive ca...
Source: Cato-at-liberty - Category: American Health Authors: Source Type: blogs
This study examined change in individually defined problem behaviors during a telephone-assisted self-help (TASH) intervention for parents of children with attention-deficit/hyperactivity disorder (ADHD). Method: Parents of children with ADHD and functional impairment despite methylphenidate treatment participated in a 12-month TASH intervention (8 self-help booklets plus up to 14 counseling telephone calls). The severity of three individually defined target problems, of ADHD symptoms, and oppositional symptoms were rated at baseline and after 6 and 12 months; parental satisfaction with the intervention was assessed after ...
Source: Zeitschrift fur Kinder- und Jugendpsychiatrie und Psychotherapie - Category: Child Development Tags: Z Kinder Jugendpsychiatr Psychother Source Type: research
As the physical coronavirus pandemic continues to spread, an emotional pandemic is following fast in its wake. When the whole world is going to pieces, it’s awfully hard for the human mind—a fragile thing in the best of times—to cope, and more and more, doctors are reporting the spread of despair, worry and depression among their patients, especially those already suffering from some form of anxiety disorder. Even before COVID-19 hit its shores, the U.S. was a clinically anxious place. According to the National Institute of Mental Health, just over 19% of all American adults will experience at least one a...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 Source Type: news
 It’s often said that fear is the most dangerous virus on the planet. While a relatively small percentage of people will contract the new coronavirus, or COVID-19, the fear it provokes will chip away at the mental health of nearly everyone who hears about it. So why does COVID-19 inspire so much fear when there are other diseases lurking in the shadows? And what can we do about it? In today’s podcast, our guest Dr. David Batman, a registered medical practitioner in the U.K., discusses how this high level of unprecedented global panic is being intensified by the non-stop media, and specifically, social media....
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Anxiety and Panic General Health-related Interview Podcast The Psych Central Show Source Type: blogs
This article reviews late-life anxiety disorders. Pharmacologic and psychotherapy approaches to treat late-life anxiety are reviewed, including a summary of current innovations in clinical care across settings, treatment models, and treatment delivery.
Source: Clinics in Geriatric Medicine - Category: Geriatrics Authors: Source Type: research
AbstractPurpose of ReviewTo discuss updates and recommendations for the treatment of postherpetic neuralgia (PHN), a painful neuropathic condition caused by reactivation of the latent varicella-zoster virus (VZV). The focus of this review will include prevention, evaluation, diagnosis, and management.Recent FindingsUsing a multidisciplinary approach to management yields the best results, including oral and topical medication, physical therapy, psychotherapy, injections, complementary, and other procedural interventions, as well as neural stimulation.SummaryRecent advancements in the management of neuropathic pain condition...
Source: Current Emergency and Hospital Medicine Reports - Category: Emergency Medicine Source Type: research
Telemedicine and e-Health, Ahead of Print.
Source: Telemedicine and e-Health - Category: Information Technology Authors: Source Type: research
Condition:   Depression Interventions:   Behavioral: Cognitive-behavioral therapy;   Behavioral: Personal Construct Therapy;   Behavioral: Personal Construct Therapy with virtual reality Sponsors:   University of Barcelona;   Universitat Oberta de Catalunya Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
More News: Clinical Trials | Diazepam | International Medicine & Public Health | Psychiatry | Psychotherapy | Students | Study | Universities & Medical Training | Valium | Warnings