003 A case of wong-type dermatomyositis with Anti-TIF1- γ antibody

We report the first case of positive anti-TIF1-γantibody in Wong-type DM associated with parotid gland tumor and demonstrated the importance of detection of serum anti-TIF1-γantibody and screening tumor in Wong-type DM. The titer of the antibody was also closely correlated with the severity of cutaneous and the prognosis of the disease. Dynamic observation of serum anti-TIF1-γantibody levels would be helpful in predicting the course and facilitating better therapeutic targeting.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Adaptive and Auto-Immunity Source Type: research