420 Investigating new molecular pathways in skin vascular formation and disease

Primary Lymphedema (PL) is an incurable, disfiguring, and often debilitating disease. It develops due to abnormalities in the formation and/or function of the lymphatic system and results in the accumulation of protein-rich fluid (lymph) in the interstitial space and swelling. Onset can vary from embryonic stages to middle age. Left untreated, lymphedema can lead to chronic and disabling infections and inflammation. Here, we present a new pathway that may identify novel targets for treatment of PL.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Genetic Disease, Gene Regulation, and Gene Therapy Source Type: research