Anaplasma bovis infection in a horse: first clinical report and molecular analysis

Publication date: Available online 18 April 2019Source: Veterinary MicrobiologyAuthor(s): Min-Goo Seo, Oh-Deog Kwon, Dongmi KwakAbstractA 23-year-old male Thoroughbred horse at the Korean Military Academy appeared thin with visible rib bones and presented clinical signs of fever, anorexia, lethargy, and severe dehydration. To determine the presence of various febrile disease-causing agents, the 23 cohabiting horses at the academy, including this horse, were subjected to hematology, blood chemistry, and molecular analysis using whole blood samples collected during regular medical check-ups. On the basis of clinical history, physical examination, hematology, blood chemistry, and fecal examination, differential diagnosis using molecular analyses was performed for various febrile disease-causing agents, including Lyme borreliae, Coxiella, piroplasms (Babesia and Theileria), Rickettsiales (Anaplasma, Ehrlichia, and Rickettsia), equine herpesvirus, equine infectious anemia virus, and equine arteritis virus. While other pathogens were not detected, PCR and phylogenetic analysis targeting the Anaplasma 16S rRNA gene revealed that the horse was infected with Anaplasma bovis. Although PCR targeting the groEL and gltA genes of A. bovis was not successful, the restriction enzyme fragment length polymorphism assay for differential diagnosis and determination of coinfectivity between Anaplasma phagocytophilum and A. bovis confirmed the pathogen as A. bovis. To the best of our knowledge, th...
Source: Veterinary Microbiology - Category: Veterinary Research Source Type: research

Related Links:

CONCLUSIONS: PheWAS is a viable tool for calculating risk associated with any biomarker. The current analysis provide a new approach to generating hypotheses and understanding the breadth of health disparities. Future analyses will further explore causality, risk factors, and potential confounders not accounted for here. PMID: 32958289 [PubMed - as supplied by publisher]
Source: Journal of the National Medical Association - Category: General Medicine Tags: J Natl Med Assoc Source Type: research
Authors: Ren X, Li X, Huo J, You Y, Huang J, Shao Y, Ge M, Huang Z, Zhang J, Wang M, Jin P, Nie N, Zheng Y Abstract Objectives: To clear the obscure conclusion on the prediction value of paroxysmal nocturnal haemoglobinuria (PNH) clones in severe aplastic anaemia (SAA) patients treated with immunosuppressive therapy (IST). Methods: We retrospectively analyzed 219 consecutive SAA patients treated with IST from October 2008 to October 2015 and evaluated the haematological responses to IST. Results: The presence of a PNH clone was detected in 55 (25.1%) patients prior to IST [37/88 by flow cytometry (FCM) and 18/131 b...
Source: Hematology - Category: Hematology Tags: Hematology Source Type: research
ConclusionsWe conclude that, in this observational “real life” study, the two EPOs are to be considered as equivalent.
Source: International Urology and Nephrology - Category: Urology & Nephrology Source Type: research
Publication date: November 2020Source: Multiple Sclerosis and Related Disorders, Volume 46Author(s): Brandy Love, Jennifer A. McCombe
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research
Tuberculosis (TB) is associated with systemic inflammation and anemia, which are aggravated in persons living with HIV (PLWH). Here, we characterized the dynamics of hemoglobin levels in PLWH coinfected with TB undergoing antitubercular therapy (ATT). We also examined the relationships between anemia and systemic inflammatory disturbance as well as the association between persistent anemia and unfavorable clinical outcomes. Data on several blood biochemical parameters and on blood cell counts were retrospectively analyzed in a cohort of 256 TB/HIV patients from Brazil during 180 days of ATT. Multidimensional statistical an...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Conditions:   Underweight;   Stunted Growth;   Wasting;   Anemia Intervention:   Dietary Supplement: Multiple-micronutrients supplement Sponsor:   Universiti Putra Malaysia Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Anorexia Nervosa Intervention:   Sponsor:   Institut National de la Santé Et de la Recherche Médicale, France Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Underweight;   Stunted Growth;   Wasting;   Anemia Intervention:   Dietary Supplement: Multiple-micronutrients supplement Sponsor:   Universiti Putra Malaysia Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Anorexia Nervosa Intervention:   Sponsor:   Institut National de la Santé Et de la Recherche Médicale, France Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Publication date: Available online 22 September 2020Source: Progress in Neuro-Psychopharmacology and Biological PsychiatryAuthor(s): Laura Di Lodovico, Stanislas Mondot, Joel Doré, Isabelle Mack, Mouna Hanachi, Philip Gorwood
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - Category: Psychiatry Source Type: research
More News: Academies | Anemia | Anorexia | Babesiosis | Chemistry | Eating Disorders & Weight Management | Genetics | Hematology | Lyme Disease | Microbiology | Veterinary Research