Anaplasma bovis infection in a horse: first clinical report and molecular analysis

Publication date: Available online 18 April 2019Source: Veterinary MicrobiologyAuthor(s): Min-Goo Seo, Oh-Deog Kwon, Dongmi KwakAbstractA 23-year-old male Thoroughbred horse at the Korean Military Academy appeared thin with visible rib bones and presented clinical signs of fever, anorexia, lethargy, and severe dehydration. To determine the presence of various febrile disease-causing agents, the 23 cohabiting horses at the academy, including this horse, were subjected to hematology, blood chemistry, and molecular analysis using whole blood samples collected during regular medical check-ups. On the basis of clinical history, physical examination, hematology, blood chemistry, and fecal examination, differential diagnosis using molecular analyses was performed for various febrile disease-causing agents, including Lyme borreliae, Coxiella, piroplasms (Babesia and Theileria), Rickettsiales (Anaplasma, Ehrlichia, and Rickettsia), equine herpesvirus, equine infectious anemia virus, and equine arteritis virus. While other pathogens were not detected, PCR and phylogenetic analysis targeting the Anaplasma 16S rRNA gene revealed that the horse was infected with Anaplasma bovis. Although PCR targeting the groEL and gltA genes of A. bovis was not successful, the restriction enzyme fragment length polymorphism assay for differential diagnosis and determination of coinfectivity between Anaplasma phagocytophilum and A. bovis confirmed the pathogen as A. bovis. To the best of our knowledge, th...
Source: Veterinary Microbiology - Category: Veterinary Research Source Type: research

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The objective of this study was to characterize AKI in dogs with babesiosis caused by Babesia rossi at presentation and after treatment. Thirty-five client-owned dogs with B. rossi infection and 10 control dogs were included in this prospective observational study. Blood and urine were collected in Babesia-infected dogs at presentation (T0, n = 35), after 24 hours (T24h, n = 11), and after 1 month (T1m, n = 9). The following urinary kidney injury biomarkers were assessed: urinary protein to creatinine ratio (UPC), urinary glomerular injury biomarkers (immunoglobulin G (uIgG)...
Source: Ticks and Tick borne Diseases - Category: Zoology Source Type: research
Publication date: Available online 19 February 2020Source: Research in Veterinary ScienceAuthor(s): Ying-Feng Sun, Xuan Jiang, Ao Zhang, Ji-Fei Ma, Xiao-Xue Yu, Liu-An Li, Hai YuAbstractModified-live virus (MLV) vaccines derived from highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) were wildly used in China, which resulted in the emergence of MLV-like strains in pigs. Previous studies demonstrated that secondary bacterial infection could enhance HP-PRRSV infection-mediated inflammatory responses, but it is unknown whether early bacterial infection could enhance the HP-PRRSV MLV-like infectio...
Source: Research in Veterinary Science - Category: Veterinary Research Source Type: research
Publication date: March 2020Source: The Lancet Global Health, Volume 8, Issue 3Author(s): Jasper Tromp, Sahiddah Bamadhaj, John G F Cleland, Christiane E Angermann, Ulf Dahlstrom, Wouter Ouwerkerk, Wan Ting Tay, Kenneth Dickstein, Georg Ertl, Mahmoud Hassanein, Sergio V Perrone, Mathieu Ghadanfar, Anja Schweizer, Achim Obergfell, Carolyn S P Lam, Gerasimos Filippatos, Sean P CollinsSummaryBackgroundHeart failure is a global public health problem, affecting a large number of individuals from low-income and middle-income countries. REPORT-HF is, to our knowledge, the first prospective global registry collecting information o...
Source: The Lancet Global Health - Category: International Medicine & Public Health Source Type: research
Conditions:   Pregnancy Related;   Anemia, Iron Deficiency;   Anemia of Pregnancy Interventions:   Drug: Ferumoxytol;   Drug: Ferrous Sulfate Sponsors:   Thomas Jefferson University;   Auerbach Hematology and Oncology Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
While partial splenic artery embolization (PSAE) is a useful procedure that has been performed for a variety of indications including trauma and hypersplenism, it has been rarely described as a treatment for idiopathic warm autoimmune hemolytic anemia (AIHA). Previous reports in the literature are limited to case reports in situations that include the patient being a poor surgical candidate, the inability to transfuse blood during surgery because of autoantibodies, and a patient ’s refusal of blood products on religious grounds.
Source: Journal of Vascular and Interventional Radiology : JVIR - Category: Radiology Authors: Tags: Scientific e-Poster Source Type: research
We present a 15-year-old boy with Evans syndrome and common variable immunodeficiency who experienced a severe, refractory flare 16 months postsplenectomy. After failing to respond to multiple other agents, he achieved a durable response to a bortezomib-based regimen. Bortezomib may be a reasonable second or third line option, especially before high-morbidity therapies such as splenectomy or stem cell transplantation.
Source: Journal of Pediatric Hematology Oncology - Category: Hematology Tags: Online Articles: Clinical and Laboratory Observations Source Type: research
ConclusionsAmyloidosis is an uncommon finding in patients with multiple myeloma, especially in younger individuals.
Source: Arab Journal of Gastroenterology - Category: Gastroenterology Source Type: research
We present a case of PVS complicating Crohn’s disease in a 38-years-old female patient under treatment with the biologic agent Ustekinumab (human interleukin 12/23 monoclonal antibody) suffering from a progressively worsening dysphagia.
Source: Arab Journal of Gastroenterology - Category: Gastroenterology Source Type: research
LYME disease is a bacterial infection which could lead to severe physical and mental problems if not diagnosed at an early stage. Spotting the early warning signs will ensure prompt treatment and noticing this peculiar feeling in the head could mean you're at risk.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Authors: Kawada T PMID: 32065257 [PubMed - as supplied by publisher]
Source: European Archives of Psychiatry and Clinical Neuroscience - Category: Psychiatry Tags: Eur Arch Psychiatry Clin Neurosci Source Type: research
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