Toonamicronoids A–D, four new B-seco-limonoids from Toona microcarpa
Publication date: June 2019Source: Phytochemistry Letters, Volume 31Author(s): Ling Zhang, Jianjun Xia, Jianyun Yang, Long Zhu, Danyu Tang, Ji Ma, Yingliang Zhao, Xiaoying Zeng, Minghua QiuAbstractFour new B-seco-limonoids, toonamicronoids A–D (1–4), together with four known ones, toonaciliatin H–J (5–7), and toonacilianin A (8), were isolated from Toona microcarpa. Their structures were identified on the basis of ESIMS, HREIMS and 1D/2D NMR analysis. Compounds 1 and 4 showed moderate cytotoxicities against HL-60 with the IC50values of 17.3 ± 1.5 and 22.7 ± 1.9 μM, respectively.Graphical abstract
Source: Phytochemistry Letters - Category: Chemistry Source Type: research
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