Core-shell lipid-polymer nanoparticles as a promising ocular drug delivery system to treat glaucoma

In conclusion, Brz-LPNs, as promising ocular drug delivery systems, are well worth developing in the future for glaucoma treatment.Graphical AbstractWe prepared the core-shell lipid-polymer nanoparticles (LPNs) as the carriers of brinzolamide (Brz-LPNs) and investigated the potential of enhancing sustained drug release, corneal permeation and intraocular pressure (IOP) reduction of Brz-LPNs.
Source: Chinese Chemical Letters - Category: Chemistry Source Type: research