Improved Lovastatin Production by Inhibiting (+)-Geodin Biosynthesis in Aspergillus terreus.

This study thus shows that suppression of the (+)-geodin pathway increases lovastatin yield and demonstrates a practical approach of manipulating carbon flux by modulating enzyme activity.
PMID: 30995533 [PubMed - as supplied by publisher]

Source: New Biotechnology - April 13, 2019 Category: Biotechnology Authors: Hasan H, Rahim MHA, Campbell L, Carter D, Abbas A, Montoya A Tags: N Biotechnol Source Type: research