Outcome of a screening program for the prevention of neonatal early-onset group B Streptococcus infection: a population-based cohort study in Inner Mongolia, China.

CONCLUSIONS: Our findings illustrate that this perinatal screening (including preterm births) for prevention of EOGBS infection can be implemented in the Inner Mongolian area. PMID: 30994439 [PubMed - as supplied by publisher]
Source: Journal of Medical Microbiology - Category: Microbiology Authors: Tags: J Med Microbiol Source Type: research

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ConclusionsRemission of type 2 diabetes 5 years after bariatric surgery was associated with improvements in albuminuria and stabilized prognostic risk for CKD, but not with eGFR. Lower kidney function and greater prognostic risk at the time of bariatric surgery was linked to a lower likelihood of diabetes remission. These results highlight the need to identify the mechanisms through which bariatric surgery may delay the long-term progression of CKD in type 2 diabetes.
Source: American Journal of Kidney Diseases - Category: Urology & Nephrology Source Type: research
Authors: Hamouda L, Miliani M, Hadjidj Z, Messali R, Aribi M Abstract BACKGROUND: Monocytes are the main blood innate mononuclear phagocyte and one of the most important effector cells expressing Fcγ receptor, which is critical for the interaction with Fc domain of antibodies. OBJECTIVE: To evaluate the effect of Rituximab (RTX, a chimeric human anti-CD20 monoclonal antibody) on the functional activities of Monocytes (MOs) at the onset of human Type 1 Diabetes (T1D). METHODS: MOs were isolated from peripheral blood mononuclear cells (PBMCs) obtained from volunteer patients with recent-onset T1D and he...
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - Category: Drugs & Pharmacology Tags: Endocr Metab Immune Disord Drug Targets Source Type: research
Authors: Wykretowicz M, Katulska K, Zwanzig M, Krauze T, Piskorski J, Guzik P, Wykretowicz A Abstract OBJECTIVES: Left atrial fibrosis represents a substrate for atrial fibrillation (AF) and cardioembolic events. White matter hyperintensities (WMH) are commonly found on magnetic resonance imaging (MRI) and are regarded, at least partly as ischemic brain lesions. Aortic excess pressure (excessPTI) represents an extra work performed by the left ventricle and is a new risk metric associated with cardiovascular complications. The aim of our study was to assessed whether there is a correlation between the degree of LA f...
Source: Scandinavian Cardiovascular Journal - Category: Cardiology Tags: Scand Cardiovasc J Source Type: research
Publication date: August 2019Source: Nutrition, Metabolism and Cardiovascular Diseases, Volume 29, Issue 8Author(s): Ilaria Calabrese, Marilena Vitale, Maria Masulli, Angela Albarosa Rivellese, Gabriele Riccardi, Olga Vaccaro
Source: Nutrition, Metabolism and Cardiovascular Diseases - Category: Nutrition Source Type: research
Publication date: October 2019Source: Journal of Functional Foods, Volume 61Author(s): Yang Yu, Zuogong Zhao, Tiehu Liu, Hua Wan, Dongnan QiAbstractThe present study investigated the protective effect of L-cysteine on biomarkers and peripheral nervous system in streptozotocin-induced diabetic rats. The experimental groups included sham, control, 0.1 mM cysteine treatment, and 0.2 mM cysteine treatment. Behavioral assessment, fasting glucose, lipid peroxidation, glutathione peroxidase, superoxide dismutase, and catalase activities, as well as reduced GSH, tumor necrosis factor (TNF), -α, interleukin-6 (IL-6), inte...
Source: Journal of Functional Foods - Category: Nutrition Source Type: research
ConclusionThere is a need to increase the awareness of MS among the PHC Physicians. More training programs need to be planned. A better awareness among primary care physician is warranted for an early diagnosis and effective management of MS in Saudi Arabia.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
Publication date: Available online 19 July 2019Source: Canadian Journal of DiabetesAuthor(s): P. Khanna, L. Chow, E. Brydges, K. Anukum, S. Liu, J.L. Mahon, T. Joy, R. McManusAbstractPregnancies complicated by diabetes are increasingly frequent. The Endocrine and Pregnancy Clinic [EPC] at St Joseph’s Health Care London is the stable, local provider of all outpatient pregnancy diabetes care, thereby providing an opportunity to document patient characteristics with time.MethodsEPC charts were reviewed for: 2000-2002; 2010-2012; 2014-2016 documenting DM type (T1DM, T2DM, GDM); age; weight; year/week of DM diagnosis; med...
Source: Canadian Journal of Diabetes - Category: Endocrinology Source Type: research
Our weekly DiabetesMine advice column takes a deep dive into seasonal allergies and their impact on blood sugar control for people with diabetes.
Source: Diabetes Mine - Category: Endocrinology Authors: Source Type: blogs
Publication date: Available online 19 July 2019Source: Pharmacological ResearchAuthor(s): Chiara Pavanello, Andrea Baragetti, Adriana Branchi, Liliana Grigore, Samuela Castelnuovo, Eleonora Giorgio, Alberico L. Catapano, Laura Calabresi, Monica GomaraschiAbstractLysosomal acid lipase (LAL) is responsible for the hydrolysis of cholesteryl esters (CE) and triglycerides (TG) within the lysosomes; generated cholesterol and free fatty acids (FFA) are released in the cytosol where they can regulate their own synthesis and metabolism. When LAL is not active, as in case of genetic mutations, CE and TG accumulate in the lysosomal c...
Source: Pharmacological Research - Category: Drugs & Pharmacology Source Type: research
This study provides support for the rapid screening of minor neuraminidase inhibitors from complex natural medicines.Graphical abstract
Source: Journal of Pharmaceutical and Biomedical Analysis - Category: Drugs & Pharmacology Source Type: research
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