Cloning, expression, and purification of the recombinant pro-apoptotic dominant-negative survivin T34A-C84A protein in Escherichia coli
In conclusion, our study provides a protocol of producing a biologically active survivin-targeting macromolecule, T34A-C84A-dNSur-His, which can be used as a tool for studying the molecular and cellular roles of survivin in cells. T34A-C84A-dNSur-His is also a potential therapeutic agent for augmenting cancer therapy.
Source: Protein Expression and Purification - Category: Biochemistry Source Type: research
More News: Adenocarcinoma | Biochemistry | Breast Carcinoma | Cancer | Cancer & Oncology | Cancer Therapy | Carcinoma | Gastroenteritis | Molecular Biology | Pancreas | Pancreatic Cancer | Study