Behavioral disorders in kids with autism linked to reduced brain connectivity

(Yale University) More than a quarter of children with autism spectrum disorder are also diagnosed with disruptive behavior disorders. For the first time, Yale researchers have identified a possible biological cause: a key mechanism that regulates emotion functions differently in the brains of the children who exhibit disruptive behavior.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news

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Authors: Westphal A, Allely C Abstract The relationship between autism spectrum disorder (ASD) and violence is poorly understood. Several violence risk factors are either modified by or are unique to ASD; clinicians conducting violence risk assessment of people with ASD must consider these factors. An ASD-specific risk assessment tool is clearly needed. In the absence of this, clinicians often use risk assessment tools designed for other populations, highlighting the importance of establishing their predictive validity in people with ASD. Girardi and colleagues have taken a very important step in this process in th...
Source: Journal of the American Academy of Psychiatry and the Law - Category: Medical Law Tags: J Am Acad Psychiatry Law Source Type: research
Conclusions and ImplicationsThese findings suggest that the narrative coherence of autistic children’s witness accounts is equivalent to TD peers of comparable age and ability.
Source: Research in Developmental Disabilities - Category: Disability Source Type: research
This study aimed to analyze the psychometric qualities of a new self-administered questionnaire (ACSo) assessing subjective complaints in different domains of social cognition from 89 patients with schizophrenia, schizoaffective disorders, bipolar disorders or autism. The results revealed satisfactory internal validity and test-retest properties allowing the computation of a total score along with four sub scores (attributional biases, social perception and knowledge, emotional perception and theory of mind). Moreover, the ACSo total score was correlated with other subjective assessments traditionally used in cognitive rem...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
When I boarded an 8-hour international flight home from a language neurobiology conference a this past August, I anticipated getting some major work done. If I was lucky, I could also catch a nap. But my plans quickly changed when assigned seating fates intervened. Thanks to a technical snafu, I got the last remaining seat on the plane. As I walked down the aisle, a flight attendant stopped me. She warned that my seatmate—a young boy with nonverbal autism prone to disruptive behaviors—might make the flight difficult, but that there were no more available seats. When I sat down, the boy’s father preemptive...
Source: American Speech-Language-Hearing Association (ASHA) Press Releases - Category: Speech-Language Pathology Authors: Tags: autism News Slider Speech-Language Pathology Augmentative Alternative Communication Autism Spectrum Disorder Source Type: blogs
ConclusionsExamination of plots of the significant interactions suggested higher levels of negative parenting may exacerbate later behavioral problems and lower levels of negative parenting may protect against later behavioral problems for children with less severe ASD symptoms but not for those with more severe ASD symptoms. Results have implications for interventions targeting parenting practices for children with ASD.
Source: Research in Autism Spectrum Disorders - Category: Psychiatry Source Type: research
Although substance use disorder (SUD) and autism spectrum disorder (ASD) are highly comorbid with other mental disorders and commonly have onset during childhood,1 little attention has been paid to their overlap. Despite limited data suggesting that up to 4% of patients with ASD also have substance-related problems,2 there are no existing guidelines, protocols, or tailored resources focused on SUD in young people with co-occurring ASD. This is concerning given that the simultaneous presence of these disorders presents unique challenges that complicate clinical care. In particular, many of the symptoms of ASD can interfere ...
Source: Journal of the American Academy of Child and Adolescent Psychiatry - Category: Psychiatry Authors: Tags: Clinical perspectives Source Type: research
Publication date: Available online 20 November 2019Source: Prostaglandins, Leukotrienes and Essential Fatty AcidsAuthor(s): Chuck T. Chen, Joseph A. Schultz, Sophie E. Haven, Breanne Wilhite, Chi-Hsiu Liu, Jing Chen, Joseph R. HibbelnAbstractDeficiency in retinoid acid receptor-related orphan receptor alpha (RORα) of staggerer mice results in extensive granule and Purkinje cell loss in the cerebellum as well as in learned motor deficits, cognition impairments and perseverative tendencies that are commonly observed in autistic spectrum disorder (ASD). The effects of RORα on brain lipid metabolism associated with...
Source: Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA) - Category: Lipidology Source Type: research
Authors: Mellema C, Treacher A, Nguyen K, Montillo A Abstract The diagnosis of Autism Spectrum Disorder (ASD) is a subjective process requiring clinical expertise in neurodevelopmental disorders. Since such expertise is not available at many clinics, automated diagnosis using machine learning (ML) algorithms would be of great value to both clinicians and the imaging community to increase the diagnoses' availability and reproducibility while reducing subjectivity. This research systematically compares the performance of classifiers using over 900 subjects from the IMPAC database [1], using the database's derived ana...
Source: Proceedings - International Symposium on Biomedical Imaging - Category: Radiology Tags: Proc IEEE Int Symp Biomed Imaging Source Type: research
Publication date: November 2019Source: The Arts in Psychotherapy, Volume 66Author(s): Celine Schweizer, Erik J. Knorth, Tom A. van Yperen, Marinus SpreenAbstractTwo instruments were developed and examined to enable treatment evaluation for art therapy (AT) with children diagnosed with Autism Spectrum Disorders (ASD). One instrument is the OAT-A (Observation in Art Therapy with a child diagnosed ASD), the other the EAT-A (Evaluation of actions of the Art Therapist during treatment of a child diagnosed ASD). Both scales were refined in a three round procedure. In each round raters (art therapists and students) observed and c...
Source: Arts in Psychotherapy - Category: Psychiatry & Psychology Source Type: research
Mutations in protocadherin 19 (PCDH19), which is on the X-chromosome, cause the brain disease Epilepsy in Females with Mental Retardation (EFMR). EFMR is also often associated with autism-like symptoms. In mice a...
Source: Molecular Brain - Category: Neuroscience Authors: Tags: Micro report Source Type: research
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