IgG Anti-ghrelin Immune Complexes Are Increased in Rheumatoid Arthritis Patients Under Biologic Therapy and Are Related to Clinical and Metabolic Markers

This study was supported by Instituto de Nutrición y Salud Kellogg's (INSK) by the funding program Apoyo a Proyectos de Investigación en Nutrición (APIN-2016) granted to ZR-C. The funding source had no involvement on the design nor any steps of the study. Conflict of Interest Statement The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Acknowledgments The authors would like to thank Instituto de Investigación en Ciencias Biomédicas and Centro de Investigación en Biología Molecular de las Enfermedades Crónicas, for kindly providing the facilities for performing some of the experiments of the study. References 1. Avina-Zubieta JA, Thomas J, Sadatsafavi M, Lehman AJ, Lacaille D. Risk of incident cardiovascular events in patients with rheumatoid arthritis: a meta-analysis of observational studies. Ann Rheum Dis. (2012) 71:1524–9. doi: 10.1136/annrheumdis-2011-200726 PubMed Abstract | CrossRef Full Text | Google Scholar 2. Dessein PH, Joffe BI, Veller MG, Stevens BA, Tobias M, Reddi K, et al. Traditional and nontraditional cardiovascular risk factors are associated with atherosclerosis in rheumatoid arthritis. J Rheumatol. (2005) 32:435–42. Available online at: http://www.jrheum.org/content/jrheum/32/3/435.full.pdf PubMed Abstract | Google Scholar 3. Graf ...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research