IgG Anti-ghrelin Immune Complexes Are Increased in Rheumatoid Arthritis Patients Under Biologic Therapy and Are Related to Clinical and Metabolic Markers

IgG Anti-ghrelin Immune Complexes Are Increased in Rheumatoid Arthritis Patients Under Biologic Therapy and Are Related to Clinical and Metabolic Markers Mildren Porchas-Quijada1, Zyanya Reyes-Castillo1*, José Francisco Muñoz-Valle2, Sergio Durán-Barragán3,4, Virginia Aguilera-Cervantes1, Antonio López-Espinoza1, Mónica Vázquez-Del Mercado4, Mónica Navarro-Meza1 and Patricia López-Uriarte1 1Instituto de Investigaciones en Comportamiento Alimentario y Nutrición, Centro Universitario del Sur, Universidad de Guadalajara, Ciudad Guzmán, Mexico 2Instituto de Investigaciones en Ciencias Biomédicas, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, Mexico 3Departamento de Reumatología, Clínica de Investigación en Reumatología y Obesidad, Guadalajara, Mexico 4Instituto de Investigación en Reumatología y del Sistema Músculo Esquelético, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, Mexico Rheumatoid arthritis (RA) is a systemic autoimmune disease associated with increased risk of cardiovascular disease and metabolic alterations. The mechanisms underlying these alterations remain unclear. Ghrelin is a gastrointestinal hormone with potent effects on food intake, body weight, metabolism, and immune response. Recent studies reported the presence of anti-ghrelin a...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research

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Source: Daily Express - Health - Category: Consumer Health News Source Type: news
From both a public health and an economic perspective, Britain performed poorly during the Covid-19 crisis in comparison with similar countries. When put to the test, many of Britain's core systems were revealed to be incapable of withstanding extra stress and demand. Written in partnership with Local Trust, this paper intends to start a conversation about how the country can move towards resilience for a more prepared and better future. It identifies five pillars that need to form the centrepiece of any approach: economic resilience; public sector resilience; community resilience; environmental resilience; and workforce resilience.
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news
BEST supplements for high blood pressure: It may be possible for a person to lower their reading with the help of supplements. Health experts and studies indicate one could be particularly beneficial. What is it?
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
CONCLUSIONS: Small bowel obstruction resulting from LAGB tubing is an uncommon complication which was reported in few cases. Although bariatric surgery currently represents the best treatment option for morbid obesity and its related- diseases, peri- and post-operative complications have always to be taken into account. KEY WORDS: Adjustable gastric band complications, Bariatric surgery, Bowel obstruction, CT scan, LAGB tube. PMID: 32945272 [PubMed - in process]
Source: Annali Italiani di Chirurgia - Category: Surgery Tags: Ann Ital Chir Source Type: research
Authors: Polistina GE, Simioli F, Imitazione P, Lanza M, Annunziata A, Fiorentino G Abstract The coronavirus disease 2019 (COVID-19) is a recent pandemic that affected more than 5 million people worldwide. Chest high resolution computed tomography (HRCT) is an essential tool in diagnosis and management of the disease. Pulmonary parenchymal opacity is a typical sign of the disease, but not the only one. Pneumothorax, pneumomediastinum, bronchiectasis and cysts are probably underrated complications of COVID-19 that can worsen prognosis, in terms of prolonged hospitalization and need of oxygen therapy. In our single c...
Source: Monaldi Archives for Chest Disease - Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research
TYPE 2 diabetes: The amount of people living with the dangerous condition of having high blood sugar levels has increased exponentially. It is imperative that one is aware of the warning signs of this condition. What are the three main symptoms to spot?
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Conclusion: Moderate quality evidence suggests that OMTh is effective for CNCP patients. There was a significant association between visceral OMTh and reduced pain severity and disability. More robust, high-quality randomized controlled trials with larger sample sizes are required to further explore the effectiveness of the OMTh in the management of CNCP. PMID: 32946545 [PubMed - as supplied by publisher]
Source: Journal of the American Osteopathic Association - Category: Complementary Medicine Tags: J Am Osteopath Assoc Source Type: research
Authors: Lora CV, Nastro M, Vay C, Famiglietti A, Rodríguez CH Abstract A rapid colorimetric method, the Andrade screening antimicrobial test, was compared with the E-test method to detect ceftazidime/avibactam (CZA) resistance in carbapenem resistant Enterobacterales clinical isolates. A 106 non-duplicated isolates (86 susceptible and 20 resistant to CZA) were chosen for validation. The sensitivity and specificity were 100%. This method investigates CZA resistance regardless of the resistance mechanism involved. It represents an economical and easy technique that can be applied to routine microbiology labor...
Source: Journal of Chemotherapy - Category: Cancer & Oncology Tags: J Chemother Source Type: research
Follicular dendritic cell sarcoma (FDCS) is a rare sarcoma, which commonly presents as a slow-growing, painless mass. There are only a few hundred reported FDCS cases, and the role for adjuvant chemo- or radiation therapy has not been established. Choosing an appropriate therapy in disseminated disease can therefore be challenging. A 26-year-old patient with FDCS was admitted with dyspnea, fever, and night sweats. He was found to have a large right hemothorax with compressive atelectasis on initial imaging. CT of the chest revealed multiple bilateral lung and pleural nodules with associated bilateral hilar adenopathy, a hy...
Source: Case Reports in Oncology - Category: Cancer & Oncology Source Type: research
We report a patient with glucagonoma differentiation into a malignant form after 13 years. A 63-year-old asymptomatic man was evaluated for an enhancing lesion at the distal pancreas. Physical examination was normal. Laboratory values were normal except for an elevated serum glucagon level (206 pg/mL, Ref. 50 –150). Somatostatin and other tumor markers were normal. A PET scan confirmed abnormal uptake at the distal pancreas, correlating with a CT scan. The patient underwent laparoscopic distal pancreatectomy with resection of a 2.6-cm mass which predominantly expressed glucagon. Serum glucagon levels n ormalized imme...
Source: Case Reports in Oncology - Category: Cancer & Oncology Source Type: research
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