The Impact of Hyperosmolality on Activation and Differentiation of B Lymphoid Cells

This study was carried out in accordance with the German Law on Care and Use of Laboratory Animals. Euthanasia and organ preparation were approved by the local authorities (Landratsamt Erlangen-Hoechstadt, Erlangen, Germany). Author Contributions LC designed the study, planned, and performed experiments, analyzed and interpreted data and wrote the manuscript. SP designed the study, interpreted data, and edited the manuscript. JT initiated the study and supported the work. H-MJ made key suggestions, assisted in the design of experiments, interpreted data and critically reviewed the manuscript. WS designed the study, planned experiments, analyzed and interpreted data and wrote and finalized the manuscript. Funding This work was supported in part, by the Deutsche Forschungsgemeinschaft (DFG) through the doctoral training program GRK1660 to H-MJ, through research grant TRR130 (project 09) to H-MJ and WS, the German Federal Ministry for Economics and Technology/DLR Forschung unter Weltraumbedingungen (50WB1624) and the Interdisciplinary Center for Clinical Research Erlangen to JT. We acknowledge support by Deutsche Forschungsgemeinschaft and Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) within the funding programme Open Access Publishing. Conflict of Interest Statement The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Supplemen...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research