Prediction and prevention of sudden cardiac death in transposition of the great arteries: A step closer

Recently, Khairy et al. investigated the pathophysiology of sudden cardiac death (SCD) in patients with dextro-transposition of the great arteries (d-TGA) and Mustard or Senning baffles [1]. Based on his findings he postulated that myocardial oxygen supply/demand mismatch may provoke ischemia related tachyarrhythmias leading to SCD. In the current issue of this journal, Khairy et al. provide for the first time histopathological evidence in favor of this theory [2]. In the last decades, drastic changes in management of patients with d-TGA have resulted in excellent survival rates and improvements in quality of life.

Source: International Journal of Cardiology - April 16, 2019 Category: Cardiology Authors: R.K. Kharbanda, N.M.S. De Groot Tags: Editorial Source Type: research