Human collectin-11 ( < i > COLEC11 < /i > ) and its synergic genetic interaction with < i > MASP2 < /i > are associated with the pathophysiology of Chagas Disease

In this study, collectin-11 plasma levels andCOLEC11 variants in exon 7 were assessed in a Brazilian cohort of 251 patients with chronic CD and 108 healthy controls. Gene-gene interactions betweenCOLEC11 andMASP2 variants were analyzed. Collectin-11 levels were significantly decreased in CD patients compared to controls (p
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research