A “simple” way for enhanced exosomes to alter gene expression: Simple but wrong–complex but right

Exosomes are a subtype of transport vesicles that are released by almost all cell types and are present in most if not all biologic fluids. Exosomes carry biologically active cargo, especially microRNA (miRNA), and can alter the phenotype of recipient cells. After the Nobel Prize in Physiology or Medicine in 2013 was awarded to 3 groups of investigators for their work on defining how cells communicate with exosomes, there was understandable enthusiasm regarding the possibility of manipulating cellular function with synthetically enhanced exosomes.
Source: The Journal of Thoracic and Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Letter to the Editor Source Type: research