Molecules, Vol. 24, Pages 1519: Natural Products in Alzheimer ’s Disease Therapy: Would Old Therapeutic Approaches Fix the Broken Promise of Modern Medicines?

This article assesses the common pharmacological targets and therapeutic principles for current and future drugs. It also underlines the merits of natural products acting through a polytherapeutic approach over a monotherapy option of AD therapy. Multi-targeting approaches through general antioxidant and anti-inflammatory mechanisms coupled with specific receptor and/or enzyme-mediated effects in neuroprotection, neuroregeneration, and other rational perspectives of novel drug discovery are emphasized.
Source: Molecules - Category: Chemistry Authors: Tags: Review Source Type: research