Association between diet quality scores, adiposity, glycemic status and nutritional biomarkers among indian population with type 2 diabetes mellitus: A cross-sectional study

ConclusionsIncreasing dietary scores are supposed to have a provoking effect on disease condition resulting into worse outcomes at higher scores. The findings from nutritional biomarkers suggested that deficiently found nutrients must be supplemented as a part of therapy to enhance the treatment benefits.
Source: Clinical Epidemiology and Global Health - Category: Epidemiology Source Type: research

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AbstractHerein we describe four patients with acquired hemophilia A (AHA) caused by factor VIII (FVIII) inhibitor and histories of dipeptidyl peptidase-4 inhibitor (DPP4-I) treatment for diabetes mellitus (DM). Drug exposure can cause a breakdown of immune tolerance to FVIII associated with CD4 T cells, resulting in the induction of autoantibodies against FVIII. In patient 1 in the present series, FVIII inhibitor disappeared after DPP4-I treatment. The DPP4-I treatment was stopped faster in patient 1 than it was in patient 2, whose FVIII inhibitor titer was higher than patient 1 ’s. Two patients died: patient 3 due t...
Source: Diabetes Therapy - Category: Endocrinology Source Type: research
Condition:   Diabetes Mellitus, Type 2 Interventions:   Dietary Supplement: Black Seed Oil;   Drug: Anti-Diabetics Sponsor:   Ain Shams University Active, not recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Pharmacists can help patients with type 2 diabetes mellitus adopt a low-carbohydrate diet and reduce their medicines load.
Source: The Pharmaceutical Journal - Category: Drugs & Pharmacology Source Type: research
This study examined the associations between risk of ASD in offspring and maternal T1D, T2D, and GDM.
Source: Obstetric Anesthesia Digest - Category: Anesthesiology Tags: Mother, Fetus, Neonate Source Type: research
Opposing effects of IL-1β/COX-2/PGE2 pathway loop on islets in type 2 diabetes mellitus. Endocr J. 2019 May 18;: Authors: Wang G, Liang R, Liu T, Wang L, Zou J, Liu N, Liu Y, Cai X, Liu Y, Ding X, Zhang B, Wang Z, Wang S, Shen Z Abstract The cyclooxygenase2 (COX-2) enzyme catalyzes the first step of prostanoid biosynthesis, and is known for its crucial role in the pathogenesis of several inflammatory diseases including Type 2 Diabetes Mellitus (T2DM). Although a variety of studies revealed that COX-2 played a role in the IL-1β induced β cell dysfunction, the molecular mechanism remains u...
Source: Endocrine Journal - Category: Endocrinology Tags: Endocr J Source Type: research
In conclusion, these results confirmed the vital regulation of GAS5/miR-222-3p/p27 axis in the endometrial carcinoma tumorigenesis. PMID: 31105847 [PubMed]
Source: American Journal of Translational Research - Category: Research Tags: Am J Transl Res Source Type: research
Authors: Fan L, Zhou W, Zhang L, Jiang D, Zhao Q, Liu L Abstract Inhibition of hypoxia/reoxygenation (H/R)-induced insult in cardiac microvascular endothelial cells (CMECs) has been considered as a promising therapeutic strategy for the treatment of ischemic cardiovascular disease. In the present study, we found that H/R significantly increased the expression of dipeptidyl peptidase (DPP)-4 in CMECs. Treatment with the DPP-4 inhibitor sitagliptin, a licensed drug used for the treatment of type 2 diabetes mellitus (T2DM), ameliorated H/R-induced oxidative stress by decreasing the expression of NOX-4 and restoring th...
Source: American Journal of Translational Research - Category: Research Tags: Am J Transl Res Source Type: research
Obesity, defined as a body mass index (BMI) of ≥ 30.0 kg/m2, is a major public health issue that contributes to significant disability, mortality, and health care costs (1,2). During the past 50 years, there has been a significant increase in the prevalence of obesity in the United States, which now affects more than one third of adults (3). P atients with obesity are at increased risk for the development of other serious medical conditions, such as type 2 diabetes mellitus (T2DM) (1,2). As such, there has been an increase in the prevalence of T2DM that mirrors that of obesity, with approximately 26 million adults in th...
Source: Journal of Vascular and Interventional Radiology : JVIR - Category: Radiology Authors: Tags: Commentary Source Type: research
Each year around 5 –10% of people with non-diabetic hyperglycaemia will develop type 2 diabetes mellitus. Diabetes prevention is a national and global public health concern. Diabetes Prevention Programmes, whic...
Source: BMC Health Services Research - Category: General Medicine Authors: Tags: Research article Source Type: research
ConclusionsAmong patients with T2DM after a recent ACS or AIS, treatment with vildagliptin was not associated with increased risks of CV death, nonfatal MI, nonfatal stroke, and hospitalization for HF.This article is protected by copyright. All rights reserved.
Source: Journal of Diabetes Investigation - Category: Endocrinology Authors: Tags: Original Article Source Type: research
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