Family History Impact on Diabetes Control and Complications Family History Impact on Diabetes Control and Complications
Is a family history of type 2 diabetes associated with an increased risk for developing diabetes and more severe disease?Endocrine Practice
This study investigated whether a newly developed smartphone game delivering individualized exercise and physical activity promotion through an elaborate storyline can generate sustained improvements in daily physical activity (steps/day).Study designThirty-six participants were enrolled in this 24-week RCT between August 2016 and April 2018. After baseline assessment, participants were randomized in equal numbers to the intervention or control condition. Data analysis was performed in May–June 2018.Setting/participantsInactive, overweight type 2 diabetes patients, aged 45–70 years, were recruited through adver...
Conditions: Poorly Controlled Diabetes Mellitus; Intensive-de-escalation Therapy; Long-term Regimen Simplification Interventions: Drug: CSII and thereafter combination therapy with wearable devices; Drug: CSII and thereafter combination therapy; Drug: Traditionally upgrading therapy Sponsor: Yanbing Li Not yet recruiting
Condition: Diabetes Mellitus, Type 2 Interventions: Dietary Supplement: Black Seed Oil; Drug: Anti-Diabetics Sponsor: Ain Shams University Active, not recruiting
New in this year's Obesity Medicine Association update, the document also explores how obesity causes cardiovascular disease, type 2 diabetes, hypertension, dyslipidemia, fatty liver, and cancer.Medscape Medical News
HOW TO get rid of visceral fat: A diet high in sugar and fat can lead to a build-up of visceral fat, increasing the risk of serious health problems such as type 2 diabetes and heart disease. But there are certain other foods you can be eating instead to reduce this type of body fat.
Pharmacists can help patients with type 2 diabetes mellitus adopt a low-carbohydrate diet and reduce their medicines load.
This study examined the associations between risk of ASD in offspring and maternal T1D, T2D, and GDM.
Opposing effects of IL-1β/COX-2/PGE2 pathway loop on islets in type 2 diabetes mellitus. Endocr J. 2019 May 18;: Authors: Wang G, Liang R, Liu T, Wang L, Zou J, Liu N, Liu Y, Cai X, Liu Y, Ding X, Zhang B, Wang Z, Wang S, Shen Z Abstract The cyclooxygenase2 (COX-2) enzyme catalyzes the first step of prostanoid biosynthesis, and is known for its crucial role in the pathogenesis of several inflammatory diseases including Type 2 Diabetes Mellitus (T2DM). Although a variety of studies revealed that COX-2 played a role in the IL-1β induced β cell dysfunction, the molecular mechanism remains u...
Authors: Hashimoto N, Nagano H, Tanaka T Abstract The tumor suppressor gene p53 is mutated in approximately more than 50% of human cancers. p53 is also referred to as the "cellular gatekeeper" or "guardian of the genome" because it protects the body from spreading mutated genome induced by various stress. When the cells receives stimuli such as DNA damage, oncogene activation, oxidative stress or undernutrition, p53 gives rise to a number of cellular responses, including cell cycle arrest, apoptosis, cellular senescence and metabolic adaptation. Related to energy metabolisms, it has been reporte...