Intraoperative quantification of meningioma cell proliferation potential using rapid flow cytometry reveals intratumoral heterogeneity

ConclusionsRapid iFC may thus become a substitute for MIB ‐1 LI. Intratumoral heterogeneity of cellular proliferative potential exists in meningiomas and is related to tumor biological characteristics such as AGR and development of pial feeders. This observation underscores the importance of standardization in the sampling method to accurately estimate t he risk of meningioma recurrence.

Source: Cancer Medicine - April 15, 2019 Category: Cancer & Oncology Authors: Soichi Oya, Shinsuke Yoshida, Tsukasa Tsuchiya, Naoaki Fujisawa, Akitake Mukasa, Hirofumi Nakatomi, Nobuhito Saito, Toru Matsui Tags: ORIGINAL RESEARCH Source Type: research