Investigation of possible aqueous phase formation during vaporization of sevoflurane
Conclusions: An increase in water concentration following vaporization of sevoflurane can only occur when the starting water content is higher than the azeotropic concentration and therefore cannot originate from the dissolved water present in the marketed product because the water concentration in Ultane®is 34 times lower than the azeotropic concentration.
Source: Journal of Anaesthesiology Clinical Pharmacology - Category: Anesthesiology Authors: Shane Varughese Vikram G Kalthod James P Petzel Hans Peter Bacher Arthur W Wallace Source Type: research