Hashimoto's Encephalopathy Presenting with Smoldering Limbic Encephalitis.

Hashimoto's Encephalopathy Presenting with Smoldering Limbic Encephalitis. Intern Med. 2019;58(8):1167-1172 Authors: Nagano M, Kobayashi K, Yamada-Otani M, Kuzuya A, Matsumoto R, Oita J, Yoneda M, Ikeda A, Takahashi R Abstract Hashimoto's encephalopathy (HE) is a steroid-responsive autoimmune encephalopathy associated with Hashimoto thyroiditis. We herein report a case of HE manifesting "smoldering" limbic encephalitis with persisting symptoms and abnormalities on examinations. Although our patient experienced partial clinical remission after treatment, hippocampal hypermetabolism on [18F] fluorodeoxyglucose positron emission tomography (FDG-PET) and subclinical seizures on video electroencephalography persisted. Hypermetabolism on FDG-PET was improved by additional prednisolone therapy. Thus, as with other autoimmune limbic encephalitis cases, HE can take a course of "smoldering" encephalitis. FDG-PET and electroencephalogram findings can reflect the disease activity degree in such patients, although with certain neurophysiological and biochemical distinctions. PMID: 30982805 [PubMed - in process]
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research

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This article is protected by copyright. All rights reserved. PMID: 27790717 [PubMed - as supplied by publisher]
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