New drug mimics benefits of ketamine for depression

A new small-molecule drug called NV-5138 has produced a rapid antidepressant response similar to that of ketamine when tested in mice.
Source: Yale Science and Health News - Category: Universities & Medical Training Source Type: news

Related Links:

ConclusionsUnemployment, perception of diabetes’ interference with daily living activities, and social support are significantly correlated with poor glycaemic control. Further studies assessing other important clinical and psychosocial factors that may influence glycaemic control are suggested. A younger age range of participants is recommended for better outcomes and interventional implementation of findings.
Source: Journal of Taibah University Medical Sciences - Category: Universities & Medical Training Source Type: research
Conclusions: Patients with a mood disorder can expect a postoperative course similar to patients without depression or anxiety. A mood disorder does not appear to be a significant risk factor for bundled payment plans to consider when developing predictive modeling for primary anatomic TSA. Level of Evidence: Level III, retrospective case-control prognostic study
Source: Current Orthopaedic Practice - Category: Orthopaedics Tags: Original Research Source Type: research
Abstract Multicellular Eukaryotes use a broad spectrum of sexual reproduction strategies, ranging from simultaneous hermaphroditism to complete dioecy (separate sexes). The evolutionary pathway from hermaphroditism to dioecy involves the spread of sterility alleles that eliminate female or male reproductive functions, producing unisexual individuals. Classical theory predicts that evolutionary transitions to dioecy are feasible when female and male sex functions genetically trade off with one another (allocation to sex functions is sexually antagonistic) and rates of self-fertilization and inbreeding depression ar...
Source: The American Naturalist - Category: Biology Authors: Tags: Am Nat Source Type: research
PMID: 31002032 [PubMed]
Source: Current Pharmaceutical Biotechnology - Category: Biotechnology Authors: Tags: Curr Pharm Biotechnol Source Type: research
Findings from a study show that it can vary in severity, which can affect the type of treatment a woman might need to recover.
Source: Washington Post: To Your Health - Category: Consumer Health News Authors: Source Type: news
This study aimed to analyze the effect of individual differences and family variables on life satisfaction and depression in the oldest old compared with the young-old. A total of 1,799 cases from an 8-year period of the Korean Welfare Panel Study (2006-2013) were analyzed. A key finding was that life satisfaction significantly increased with time for the two groups of older adults while depression decreased. Moreover, family relationship satisfaction significantly affected both life satisfaction and depression in both groups. However, its impact was stronger for the oldest old. Finally, individual difference variables, th...
Source: International Journal of Aging and Human Development - Category: Geriatrics Tags: Int J Aging Hum Dev Source Type: research
Authors: Ishihara Y, Sugawa T, Kaneko H, Hiroshima-Hamanaka K, Amano A, Umakoshi H, Tsuiki M, Kusakabe T, Satoh-Asahara N, Shimatsu A, Tagami T Abstract We herein report two cases of patients with thyroid storm with a delayed diagnosis due to psychosis. The patients were a 63-year-old woman with bipolar II disorder and a 37-year-old man with major depressive disorder. The psychoses in both patients were well controlled with medication. Although they both showed symptoms of thyrotoxicosis, the symptoms were ignored, presumably because the psychological manifestations of worsening of psychosis and thyroid storm are s...
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
OBJECTIVES: The purpose of this study was to examine the relationship between sleep problems and suicidal ideation in depressive patients. BACKGROUND AND AIMS: Evidence from diverse settings and populations indicates that sleep problems are associated with...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Distraction, Fatigue, Chronobiology, Vigilance, Workload Source Type: news
Sexual violence occurs in all gender, socioeconomic, religious, and ethnic groups. The trauma of sexual violence negatively affects both a person's physical and mental health. Individuals often experience suicidal ideations in the aftermath of a sexually v...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
BACKGROUND: As increasing research demonstrates that military sexual trauma (MST) is associated with suicidal ideation and attempts, discerning factors that place MST survivors at risk for these outcomes is critical. The present study aimed to: (1) charact...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
More News: Depression | Health | Science | Universities & Medical Training | Yale