Technology to keep dementia patients out of hospital

Radar technology and tiny brain-monitors are just some of the devices being tested by a new research centre.
Source: BBC News | Health | UK Edition - Category: Consumer Health News Source Type: news

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Karin Meissner1,2*, Nicola Talsky1, Elisabeth Olliges1,2, Carmen Jacob1,3,4, Oliver J. Stötzer5, Christoph Salat5, Michael Braun6 and Raluca Flondor1 1Institute of Medical Psychology, Faculty of Medicine, LMU Munich, Munich, Germany 2Division of Health Promotion, Coburg University of Applied Sciences, Coburg, Germany 3Clinical Neurosciences, Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom 4Wessex Neurological Centre, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom 5Haematology and Oncology, Outpatient Cancer Ca...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Conclusion: Some patients with psychiatric syndromes and increased ANA titers may suffer from psychiatric variants of SLE, even if the American College of Rheumatology criteria for SLE are not met. Whether the psychiatric symptoms in our patient represent a prodromal stage with the later manifestation of full-blown SLE or a subtype of SLE with isolated CNS involvement remains unclear. Regardless, early diagnosis and initiation of immunosuppressive treatment are essential steps in preventing further disease progression and organ damage. Intrathecal ANAs with extractable nuclear antigen differentiation may be a more sensitiv...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Conclusions: The surrogates were more agreeable to considering assisted dying in the setting of advanced dementia than the physicians, and about half of the participants in both groups reported CDS to be an appropriate option for this population.Neurodegener Dis
Source: Neurodegenerative Diseases - Category: Neurology Source Type: research
Source: BMJ Comments - Category: General Medicine Source Type: forums
Conclusions: This study represents the first implementation of accessibility settings for dementia in mainstream apps, whilst demonstrating the feasibility and positive impact of the approach. The findings reveal core principles of touchscreen interaction and design for dementia that can inform future app development.Gerontology
Source: Gerontology - Category: Geriatrics Source Type: research
Publication date: 23 April 2019Source: Cell Reports, Volume 27, Issue 4Author(s): Brittany N. Flores, Xingli Li, Ahmed M. Malik, Jose Martinez, Asim A. Beg, Sami J. BarmadaSummaryThe majority of individuals with amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) exhibit neuronal cytoplasmic inclusions rich in the RNA binding protein TDP43. Even so, the relation between the RNA binding properties of TDP43 and neurodegeneration remains obscure. Here, we show that engineered mutations disrupting a salt bridge between the RNA recognition motifs of TDP43 interfere with RNA binding and eliminate the recog...
Source: Cell Reports - Category: Cytology Source Type: research
Publication date: Available online 24 April 2019Source: Neuroscience &Biobehavioral ReviewsAuthor(s): Yinan Zhao, Yanguo Xin, Su Meng, Zhiyi He, Wenyu HuAbstractThe diagnostic value of neurofilament light chain protein in neurodegenerative dementia diseases is still controversial. A systematic literature search was performed to identify relevant case-control studies conducted through October 2018. Traditional and net meta-analyses were performed based on 42 studies that tested the diagnostic performance of neurofilament light chain protein (NfL) concentration in CSF and serum/plasma from patients with neurodegenerative...
Source: Neuroscience and Biobehavioral Reviews - Category: Neuroscience Source Type: research
Conditions:   Alzheimer Dementia;   Agitation,Psychomotor Interventions:   Device: Electroconvulsive Therapy (ECT);   Other: Simulated Electroconvulsive Therapy (S-ECT) Sponsors:   Brent Forester;   Mayo Clinic;   Pine Rest Christian Mental Health Services;   Emory University;   The Zucker Hillside Hospital;   Medical University of South Carolina Not yet recruiting
Source: - Category: Research Source Type: clinical trials
Conditions:   Dementia;   Inflammation;   Mild Cognitive Impairment;   Cognitive Decline;   SCD;   Cognitive Dysfunction;   Pathologic Processes;   Brain Diseases;   Central Nervous System Diseases;   Nervous System Diseases;   Neurocognitive Disorders;   Mental Disorder;   Cognition  Disorders Interventions:   Dietary Supplement: Omega-3 capsules;   Dietary Supplement: Olive oil Sponsors:   University Hospital, Akershus;   BASF&nb...
Source: - Category: Research Source Type: clinical trials
In recent years, with the enthusiastic adoption of accelerometers by the designers of epidemiological studies, it has become clear that even quite modest levels of physical activity correlate strongly with improved health and a slower pace of age-related degeneration. In most human data there is no way to establish which of these is cause and which of these is consequence, but animal studies are quite definitive on the point that exercise produces improvements in health, even if it doesn't appear to extend life span. Physical activity, like all interventions, has a dose-response curve, and there is a sizable difference bet...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
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