Hospital patients' hands are covered in antibiotic resistant superbugs, study suggests 

Hospital patients may be fueling the spread of antibiotic resistance as 10 percent of their hands are teeming with superbugs shortly after admission, a new University of Michigan study suggests.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

Related Links:

In this study, we firstly tested the effects of QJSB on leucopenia using mice induced by cyclophosphamide. Our results suggested that QJSB significantly raised the number of peripheral white blood cells, platelets and nucleated bone marrow cells. Additionally, it markedly enhanced the cell viability and promoted the colony formation of bone marrow mononuclear cells. Furthermore, it reversed the serum cytokines IL-6 and G-CSF disorders. Then, using transcriptomics datasets and metabonomic datasets, we integrated transcriptomics-based network pharmacology and metabolomics technologies to investigate the mechanism of action o...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Charmaine N. Nganje, PREP scholar at Tufts University in Boston. Credit: Katherine Suarez. Charmaine N. Nganje Hometown: Montgomery Village, Maryland Influential book : The Harry Potter series (not exactly influential, but they’re my favorite) Favorite movie/TV show: The Pursuit of Happyness/The Flash Languages: English (and a bit of Patois) Unusual fact: I’m the biggest Philadelphia Eagles fan from Maryland that you’ll ever meet Hobbies: Off-peak traveling Q. Which NIGMS program are you involved with? A. The Postbaccalaureate Research Education Program (PREP)  at the Sac...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - Category: Research Authors: Tags: Being a Scientist Bacteria Diseases Infection Infectious Disease Infectious Diseases Training Source Type: blogs
Authors: Khien VV, Thang DM, Hai TM, Duat NQ, Khanh PH, Ha DT, Binh TT, Dung HDQ, Trang TTH, Yamaoka Y Abstract Antibiotic resistance is the most important factor leading to the failure of eradication regimens. This review focuses on the prevalence of Helicobacter pylori primary and secondary resistance to clarithromycin, metronidazole, amoxicillin, levofloxacin, tetracycline, and multidrug in Vietnam. We searched the PubMed, EMBASE, Vietnamese National Knowledge Infrastructure, and Vietnamese Biomedical databases from January 2000 to December 2016. The search terms included the following: H. pylori infection, anti...
Source: Gut and Liver - Category: Gastroenterology Tags: Gut Liver Source Type: research
ConclusionThese results are suggestive that the R-plasmids could possess substrate for capsaicinoids-like compounds and for their ability to inhibit the plasmid conjugation processes. Plant natural products possess the potential value of antibacterial and mechanistic antiplasmid activity as demonstrated by the compounds and should be evaluated in developing antimicrobial leads to novel mechanism against multidrug resistant bacteria.Graphical abstract
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
ACS Applied Materials&InterfacesDOI: 10.1021/acsami.9b02643
Source: ACS Applied Materials and Interfaces - Category: Materials Science Authors: Source Type: research
In this study we examined the influence of ultra-small gold and magnetite‑gold nanoparticles (NPs) stabilized with d,l-methionine, Fe3O4@Au@Met, on their antibacterial efficacy against three of twelve the worst bacterial family members included in the World Health Organization (WHO) list. In particular, gram-negative Acinetobacter baumannii, Salmonella enterica and gram-positive methicillin-resistant Staphylococcus aureus and Micrococcus luteus were tested. Apart from the synthesis, gold species reduction and NP stabilization, an excess of methionine has been used herein to detach ultra-small gold NPs from the Fe3O4@Au@M...
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research
This study identified prophages as mediators of bacterial virulence in a model of infectious endocarditis, probably through promotion of interaction with extracellular matrix components. Further studies are needed to identify mechanisms leading to promotion of intrinsic virulence. Introduction Challenges related to Staphylococcus aureus infections in the human and veterinary clinics mobilized important human and technical resources. S. aureus can colonize 20–30% of the general population asymptomatically but is also capable of causing a wide spectrum of diseases ranging from benign infections, to particularly...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Conclusion: To the best of our knowledge, this study provides the first evidence for polymorphisms of the class 1 integron variable promoter in clinical Proteus isolates, which generally contain relatively strong promoters. Resistance genotypes showed a higher coincidence rate with the drug-resistant phenotype in strong-promoter-containing strains, resulting in an ability to confer strong resistance to antibiotics among host bacteria and a relatively limited ability to capture gene cassettes. Moreover, strains with relatively weak integron promoters can “afford” a heavier “extra-integron antibiotic resist...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Conclusion This study confirms the in vitro antibacterial activity of BIOCITRO® against Gram-negative and Gram-positive bacteria. For most of the strains, the product reached the bactericidal effect at the same concentration of the bacteriostatic effect and maximum difference between MIC and MBC was two dilution steps. The less susceptible species of the study were S. enterica ssp. enterica and E. coli with MBC90 values of 256 and 128 μg/mL, respectively, while the most susceptible was C. perfringens with MBC90 of 16 μg/mL. After short exposition time to the product, the significant effect over the viability of ...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Speaking at the first Time 100 Summit in New York City on Tuesday, prominent geneticist George Church admitted that for about 10 years, he knew biological weapons could be specifically targeted to individual people. But he kept it to himself. Church, a professor of genetics at Harvard Medical School, participated in a panel discussing how to introduce breakthroughs in medicine, which can become life-saving miracles, in ethical and responsible ways. He discussed his decision not to share his knowledge widely as an example of a line he consciously decided not to cross for ethical reasons. “I kept that a secret and didn...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized 2019 TIME 100 t100summit Source Type: news
More News: Health | Hospitals | Infectious Diseases | Study | Superbugs