Endothelial-Dependent and Independent Vascular Relaxation Effect of Tetrahydropalmatine on Rat Aorta

This study was supported by the Science and Technology Commission of Shanghai (16ZR1437600), Shanghai Hospital Development Center (SHDC12015313), Shanghai University of Traditional Chinese Medicine (A1-U1720501030101), National Natural Science Foundation of China (81603549, 81673726, and 81760860), and National Health Commission of Shanghai [GWIV-28 and ZY-(2018-2020)-FWTX-8001]. Conflict of Interest Statement The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Supplementary Material The Supplementary Material for this article can be found online at: https://www.frontiersin.org/articles/10.3389/fphar.2019.00336/full#supplementary-material References Armario, P., Calhoun, D. A., Oliveras, A., Blanch, P., Vinyoles, E., Banegas, J. R., et al. (2017). Prevalence and clinical characteristics of refractory hypertension. J. Am. Heart Assoc. 6:e007365. doi: 10.1161/JAHA.117.007365 PubMed Abstract | CrossRef Full Text | Google Scholar Cao, G., Zhang, Y., Zhu, L., Zhu, J., Zhao, N., Dong, N., et al. (2018). The inhibitory effect of levo-tetrahydropalmatine on the methamphetamine-induced spatial memory impairment in mice. Neurosci. Lett. 672, 34–39. doi: 10.1016/j.neulet.2018.02.018 PubMed Abstract | CrossRef Full Text | Google Scholar Chueh, F. Y., Hsieh, M. T., Chen, C. F., and Lin, M. T. (1995). Hypotensive and bradycardic effects of dl-t...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research