Editorial: Cancer Metabolism: Current Knowledge and Perspectives

Editorial: Cancer Metabolism: Current Knowledge and Perspectives Leonardo Freire-de-Lima1*, Lucia Mendonça-Previato1* and Luciana Boffoni Gentile2* 1Laboratorio de Glicobiologia, Instituto de Biofisica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil 2Laboratório de Patologia Clínica Veterinária, Hospital Universitário de Medicina Veterinária Professor Firmino Mársico Filho (Huvet), Universidade Federal Fluminense, Rio de Janeiro, Brazil Editorial on the Research Topic Cancer Metabolism: Current Knowledge and Perspectives Over the first half of the twentieth century, it has been demonstrated that an important hallmark of cancer cells is the reprogramming of cellular metabolism. The capacity to obtain nutrients from an extremely poor microenvironment and utilize it to both generate biomass and maintain the cellular viability is a major feature of transformed cells. Several papers have proposed new mechanisms by which cancer cells undergo substantial metabolic reprogramming to endure within the hostile microenvironment. However, the metabolic profile adopted by cancer cells with invasive and multidrug-resistance phenotypes is still poorly understood. The research topic “Cancer Metabolism: Current Knowledge and Perspectives” provides exciting articles on the valuable field of cancer metabolism, where one hypothesis and theory, two original researches ...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research