The central role of psychopathology and its association with disease severity in inflammatory bowel disease and irritable bowel syndrome.

The central role of psychopathology and its association with disease severity in inflammatory bowel disease and irritable bowel syndrome. Riv Psichiatr. 2019 Mar-Apr;54(2):75-83 Authors: Piacentino D, Cesarini M, Badiali D, Pallotta N, Biondi M, Corazziari ES Abstract BACKGROUND: Biopsychosocial models for both organic and functional gastrointestinal (GI) disorders can be found in the literature. To clarify the role of psychopathological factors and their relationship with GI symptom severity, several studies have examined them in inflammatory bowel disease (IBD) - occasionally distinguishing between ulcerative colitis (UC) and Crohn's disease (CD) - and in irritable bowel syndrome (IBS), leading to unclear results. AIMS: We aimed to evaluate the psychopathological features of IBD and IBS patients in comparison with healthy individuals and assess the association with disease severity. MATERIALS AND METHODS: Sixty-nine IBD outpatients, of which 35 UC and 34 CD, and 75 IBS ones were consecutively recruited at the third level Gastroenterological Center of our University Hospital; 76 healthy controls were also recruited. The psychological status was assessed with the Symptom Checklist-90-Revised (SCL-90-R). RESULTS: IBD and IBS patients showed significantly higher scores on the SCL-90-R Global Severity Index (GSI) and subscales than controls (all p-values
Source: Rivista di Psichiatria - Category: Psychiatry Tags: Riv Psichiatr Source Type: research

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Publication date: Available online 12 December 2019Source: Journal of the Formosan Medical AssociationAuthor(s): I Chun Ma, Wei Hung Chang, Chen-Long Wu, Chih-Hao LinBackgroundFew studies have explored the field experiences and risk factors related to post-traumatic stress disorder (PTSD) among disaster rescue workers.MethodsA 6.4-magnitude earthquake struck southern Taiwan on February 6, 2016. A standardized, paper-based, self-administered survey questionnaire including demographic information, field experiences and the Post-Traumatic Stress Disorder Checklist (PCL) was conducted among emergency medical technicians (EMTs)...
Source: Journal of the Formosan Medical Association - Category: General Medicine Source Type: research
ConclusionsWe hypothesize that itaconate transiently inhibits SDH to gradually “awaken” mitochondrial function upon reperfusion that minimizes ROS and tissue damage. Collectively, our data indicate that itaconate acts as a mitochondrial regulator that controls redox metabolism to improve physiological outcomes associated with IR injury.
Source: Molecular Metabolism - Category: Endocrinology Source Type: research
Publication date: Available online 12 December 2019Source: Pharmacological ResearchAuthor(s): Ziqian Cheng, Ranji Cui, Tongtong Ge, Wei Yang, Bingjin LiAbstractOptogenetics is a biological technique, which involves controlling the biological functions of target cells using light. In recent years, optogenetics has become one of the most advanced experimental techniques in neuroscience. It provides precise control on target cells in addition to rapidly and specifically altering the neuronal activity both in vivo and ex vivo. The emergence of optogenetic technology enabled researchers to study the pathogenesis of diseases at ...
Source: Pharmacological Research - Category: Drugs & Pharmacology Source Type: research
ConclusionThe results support that EO ‘aromatherapy’ can promote dose-dependent regulation of anxiety, depression and OSI and that efficacy requires optimization of dose.Graphical abstract
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 12 December 2019Source: Journal of Pharmaceutical AnalysisAuthor(s): Wajid Ali Khan, Muhammad Balal Arain, Yadollah Yamini, Nasrullah Shah, Tasneem Gul Kazi, Stig Pedersen-Bjergaard, Mohammad TajikAbstractHollow-fiber liquid-phase microextraction (HF-LPME) and electromembrane extraction (EME) are miniaturized extraction techniques, and have been coupled with various analytical instruments for trace analysis of heavy metals, drugs and other organic compounds, in recent years. HF-LPME and EME provides high selectivity, efficient sample cleanup and enrichment, and reduces the consumption of ...
Source: Journal of Pharmaceutical Analysis - Category: Drugs & Pharmacology Source Type: research
(Reuters Health) - While army suicides have historically decreased during wartime, that trend appears to have reversed in recent decades, a new study of U.S. records finds.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
By just engaging in the basic strategies in the Wheat Belly Total Health, Wheat Belly 10-Day Grain Detox, or Undoctored programs, many mild cases of small intestinal bacterial overgrowth, SIBO, reverse. These efforts thereby restore your ability to ingest prebiotic fibers without diarrhea, bloating, gas, abdominal discomfort, joint pain, and dark emotional feelings. Many people thereby are relieved of irritable bowel syndrome symptoms, fibromyalgia, or restless leg syndrome, or have greater power in reversing autoimmune conditions such as rheumatoid arthritis. Unfortunately, not everybody enjoys reversal of SIBO with our b...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: SIBO grain-free probiotic undoctored wheat belly Source Type: blogs
ConclusionIBD/IBS+ affect scoring of IBD disease activity scales and become less useful in guiding treatment plans.
Source: Digestive Diseases and Sciences - Category: Gastroenterology Source Type: research
Conclusions: The prevalence of IBS-like symptoms in inactive IBD patients was significantly higher than in healthy controls. Inactive CD patients with IBS-like symptoms has low QOL and anxiety; suggesting that anxiety may be associated with symptom development in such patients. PMID: 27193973 [PubMed - as supplied by publisher]
Source: Journal of Neurogastroenterology and Motility - Category: Gastroenterology Tags: J Neurogastroenterol Motil Source Type: research
Director chair, film slate and load horn. Here’s a proposal for you: If, by following the Wheat Belly lifestyle, a long list of conditions are reduced or reversed at no risk, almost no cost, reversing even chronic and potentially fatal conditions . . . does that mean that the notion of self-directed health might be on the horizon, i.e., putting control over health back in our own hands? I think it does. No, we will never implant our own defibrillators or take out our own gallbladders. But so many chronic health conditions afflicting modern humans recede that I believe that it is entirely reasonable to start talking a...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Wheat Belly Lifestyle arthritis autoimmune diabetes eating disorder gluten grains Inflammation joint Weight Loss Source Type: blogs
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