Characterization of the Early Life Microbiota Development and Predominant Lactobacillus Species at Distinct Gut Segments of Low- and Normal-Birth-Weight Piglets

Characterization of the Early Life Microbiota Development and Predominant Lactobacillus Species at Distinct Gut Segments of Low- and Normal-Birth-Weight Piglets Na Li, Shimeng Huang, Lili Jiang, Zhaolai Dai, Tiantian Li, Dandan Han and Junjun Wang* State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, China Microbial exposure during early life plays a pivotal role in modulating the health and intestinal development of the host. Our recent study showed that the low-birth-weight (LBW) piglets harbored a different fecal microbiota compared to normal-birth-weight (NBW) piglets during early life with a lower abundance of the genus Lactobacillus. Considering the spatial variations in gut microbiota at distinct gut locations, this study was designed to further investigate the differences in the microbiota composition and predominant Lactobacillus species in the ileum and colon between LBW and NBW piglets during early life, including day 7 (D7), day 21 (D21, before weaning), and day 35 (D35, 2 weeks after weaning). Compared with the normal group, LBW piglets harbored a significantly lower proportion of short-chain fatty acids producing microbes, such as Ruminococcaceae and Prevotellaceae in the ileum on D7, Alistipes and Lachnospiraceae in the colon on D7, Blautia in the colon on D21, and Ruminiclostridium 9 in the colon on D35. The relative abundance of the phylum Bacteroidetes was also declined in both i...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research

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Publication date: Available online 18 November 2019Source: Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of LipidsAuthor(s): Zhen Wang, Hui Gyu Park, Dong Hao Wang, Riki Kitano, Kumar S.D. Kothapalli, J. Thomas BrennaAbstractBranched chain fatty acids (BCFA) and linear chain/normal odd chain fatty acids (n-OCFA) are major fatty acids in human skin lipids, especially sebaceous gland (SG) wax esters. Skin lipids contain variable amounts of monounsaturated BCFA and n-OCFA, in some reports exceeding over 20% of total fatty acids. Fatty acid desaturase 2 (FADS2) codes for a multifunctional enzyme that catalyz...
Source: Biochimica et Biophysica Acta (BBA) Molecular and Cell Biology of Lipids - Category: Lipidology Source Type: research
ConclusionsThe median h-index for an academic thoracic surgeon in Canada and the United States is 10. Surgeons who engage in Twitter activity are more likely to have their research cited by others.
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
This study evaluated outcomes associated with treatment strategies for this nonagenarian population.MethodsTreatment and overall survival for patients 90 years and older with NSCLC in the National Cancer Data Base (2004-2014) were evaluated using logistic regression, the Kaplan-Meier method, and multivariable Cox proportional hazard models.ResultsThe majority (n = 4152, 57.6%) of the 7205 patients 90 years or older with stage I-IV NSCLC did not receive any therapy. For the entire cohort, receiving treatment was associated with significantly better survival when compared with no therapy (5-year survival, 9.3% [95% confidenc...
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
ConclusionsThe delay in surgical resection of StageIIIa NSCLC is not associated increased early mortality, however it is associated with worse 3-year post-resection survival.
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
Conclusion. The hexane extract of L. apiculata leaves showed the lower MIC against S. aureus when compared with extracts obtained from other parts of the plant. The growth curve and the colonies count suggest a bacteriostatic activity of the L. apiculata leaves extract against Staphylococcus aureus. PMID: 31737073 [PubMed]
Source: International Journal of Microbiology - Category: Microbiology Tags: Int J Microbiol Source Type: research
Publication date: Available online 18 November 2019Source: Innovative Food Science &Emerging TechnologiesAuthor(s): Oscar G. Martínez-Moreno, Luis M. Anaya-Esparza, Jorge A. Sánchez-Burgos, Libier Meza-Espinoza, Alejandro Pérez-Larios, J. Emanuel Bojorquez-Quintal, Efigenia Montalvo-GonzálezAbstractThe combined effect of vacuum, heat and ultrasound (vacuum-thermosonication, VTS) on soursop puree was investigated with regard to the viability of Escherichia coli and Staphylococcus aureus, inactivation of polyphenol oxidase and sensory quality. The VTS conditions were: vacuum (8.46, 11 and 16.9...
Source: Innovative Food Science and Emerging Technologies - Category: Food Science Source Type: research
Publication date: Available online 19 November 2019Source: Food ChemistryAuthor(s): Shaimaa Selim, Eman HusseinAbstractThe effect of including sugar beet pulp (SBP) in laying hen diets on performance, egg quality, blood chemistry and egg lipid peroxidation was studied. A total of 200 laying hens were randomly assigned into 4 groups and were offered diets containing SBP at the level of 0%, 3%, 5% and 7%. The dietary inclusion of SBP linearly (P
Source: Food Chemistry - Category: Food Science Source Type: research
PMID: 31736395 [PubMed - in process]
Source: Canadian Journal of Dietetic Practice and Research - Category: Nutrition Authors: Tags: Can J Diet Pract Res Source Type: research
In conclusion, Trypanosoma species express a copper-transporting P1B-1-type ATPase and together with other copper-binding proteins identified in the genomes of kinetoplastid parasites may constitute potential targets for anti-trypanosomal drug discovery.Graphical abstract
Source: Molecular and Biochemical Parasitology - Category: Parasitology Source Type: research
Publication date: Available online 18 November 2019Source: Antiviral ResearchAuthor(s): Wanyu Dong, Wenting Xie, Yunbo Liu, Baokun Sui, Hao Zhang, Liran Liu, Yubei Tan, Xiaohan Tong, Zhen F. Fu, Ping Yin, Liurong Fang, Guiqing PengAbstractEmerging coronaviruses (CoVs) primarily cause severe gastroenteric or respiratory diseases in humans and animals, and no approved therapeutics are currently available. Here, A9, a receptor tyrosine kinase inhibitor (RTKI) of the tyrphostin class, is identified as a robust inhibitor of transmissible gastroenteritis virus (TGEV) infection in cell-based assays. Moreover, A9 exhibited potent ...
Source: Antiviral Therapy - Category: Virology Source Type: research
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