Genomic Characterization of Arcobacter butzleri Isolated From Shellfish: Novel Insight Into Antibiotic Resistance and Virulence Determinants

Conclusion Genomic analyses herein performed allowed us to confirm the recently (Pérez-Cataluña et al., 2018a,b) suggested amendment of A. butzleri as Al. butzlerii, comb. nov. Antimicrobial susceptibility tests defined Ab 55 and Ab 6V strains as resistant to vancomycin, tetracyclin, nalidixic acid (only Ab 55 whereas Ab 6V is intermediate resistant), erythromycin, and β-lactam antibiotics. Moreover, in our strains isolated from shellfish, we identified numerous virulence, antibiotic, and heavy metal resistance determinants, also additional to those previously found in the genome sequenced A. butzleri ED-1, isolated from fuel cell, and in the A. butzleri type strain RM 4018, isolated from human gastroenteritis (Miller et al., 2007; Pérez-Cataluña et al., 2018a), leading to hypothesize that shellfish strain may be potentially more virulent. The findings of food-related A. butzleri support both epidemiological surveillance and food safety risk assessment and management in the shellfish industry. Further analysis in our laboratories is ongoing to sequence and characterize other A. butleri strains isolated from shellfish and from other food matrices, in order to obtain an updated description of the species and to clarify the role of genetic endowment, as well as of the ecological niches the strain come from, in the pathogenesis of A. butzleri. The genomic sequences here presented, and the novel insights obtained in the present study appreciabl...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research

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Hello, Is Any one getting refunds from LA LAU CONSULTANTS, which paid for WREB patient. Now that it is all in Manikin, are you getting refunds from him? He is giving me lot of trouble, basically he does not want to return money. Please let me know any one having same problem. Thank you. Here is his address. LU LAU CONSULTANTS Eric Gonzales 2835 Inez Street Los Angeles, California 90023 United States 2133698640
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: International Dental Source Type: forums
Thread Starter How to get into Specialty training (ST1) Follow 16 minutes ago 16m ago I am British Medical student , studying abroad in Bulgaria I am in my final year , i graduate with Full GMC registration , my course is 6 years. my plan is to apply directly to standalone FY2 , then get into Cardiotho...
Source: The Student Room - Category: Universities & Medical Training Authors: Tags: Medicine Source Type: forums
Publication date: Available online 24 May 2020Source: Journal of the American College of RadiologyAuthor(s): Donald Chan, Surav Sakya, Cory M. Pfeifer
Source: Journal of the American College of Radiology - Category: Radiology Source Type: research
ConclusionThe proposed multiparametric MRI-based SLICs+MTh method performs noninvasive assessment of NACT response in osteosarcoma that may improve cancer treatment monitoring, planning, and overall prognosis.Key Points• The simple linear iterative clustering supervoxels and Otsu multithresholding-based technique (SLICs+MTh) successfully estimates the proportion of necrosis, viable tumor, and edema in osteosarcoma in the course of chemotherapy.• The proposed technique is noninvasive and uses multiparametric MRI to measure necrosis as an indication of anticancer treatment response.• SLICs+MTh-based necrosis w...
Source: European Radiology - Category: Radiology Source Type: research
ConclusionsThe e-ASPECTS software generates robust values for e-ASPECTS and acute infarct volumes when using ST ≤ 4 mm with ST = 1 mm yielding the best performance for predicting baseline stroke severity and clinical outcome after 90 days.Key Points•Clinical utility of automatically derived ASPECTS from computed tomography scans was shown in patients with acute ischemic stroke and treatment with mechanical thrombectomy.•Thin slices (=  1 mm) had the highest clinical utility in comparison with thicker slices (2–10 mm) by having the strongest correlation...
Source: European Radiology - Category: Radiology Source Type: research
Publication date: Available online 25 May 2020Source: Academic RadiologyAuthor(s): Amel Amalou, Baris Turkbey, Sheng Xu, Evrim Turkbey, Peng An, Gianpaolo Carrafiello, Anna Maria Ierardi, Robert Suh, Hayet Amalou, Bradford J. Wood
Source: Academic Radiology - Category: Radiology Source Type: research
Publication date: Available online 25 May 2020Source: Personality and Individual DifferencesAuthor(s): Dean Fido, Nadja Heym, Claire A.J. Bloxsom, Kirsty A. Hunter, Michael Gregson, Alexander Sumich
Source: Personality and Individual Differences - Category: Psychiatry & Psychology Source Type: research
CONCLUSIONS: The average patient is middle aged (often male) with a history of subacute back pain, sometimes presenting fever and/or neurological damage on diagnosis. Acute phase reactants are frequently raised. Diabetes mellitus, endocarditis and immunosuppressed patients may have the worst chance of a good outcome, therefore these patients should be more carefully managed (always try to obtain an imaging-guided biopsy, correct antibiotic treatment, and a functional and clinical follow-up). PMID: 32446680 [PubMed - as supplied by publisher]
Source: Medicina Clinica - Category: General Medicine Tags: Med Clin (Barc) Source Type: research
"The doctors were shocked. They said they had never seen anything like this," says Valentina Vigilante, recalling the terrifying day her 6-year-old son Nicol ò was rushed into intensive care in Bergamo, northern Italy as he struggled to breathe.
Source: - Health - Category: Consumer Health News Source Type: news
Source: BMJ Comments - Category: General Medicine Source Type: forums
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