Sleep Is Compromised in −12° Head Down Tilt Position

Sleep Is Compromised in −12° Head Down Tilt Position Alessa L. Boschert1*, David Elmenhorst2,3, Peter Gauger1, Zhili Li4, Maria T. Garcia-Gutierrez5, Darius Gerlach1, Bernd Johannes1, Jochen Zange1, Andreas Bauer2,6 and Jörn Rittweger1,7 1Department of Muscle and Bone Metabolism, German Aerospace Center (DLR), Institute of Aerospace Medicine, Cologne, Germany 2Forschungszentrum Jülich, Institute of Neuroscience and Medicine (INM-2), Jülich, Germany 3Division of Medical Psychology, University of Bonn, Bonn, Germany 4State Key Laboratory of Space Medicine Fundamentals and Application, China Astronaut Research and Training Center, Beijing, China 5High Studies Center Alberta Gimenez (CESAG) University of Comillas, Palma de Mallorca, Spain 6Neurological Department, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Germany 7Department of Pediatrics and Adolescent Medicine, University of Cologne, Cologne, Germany Recent studies are elucidating the interrelation between sleep, cranial perfusion, and cerebrospinal fluid (CSF) circulation. Head down tilt (HDT) as a simulation of microgravity reduces cranial perfusion. Therefore, our aim was to assess whether HDT is affecting sleep (clinicaltrials.gov; identifier NCT 02976168). 11 male subjects were recruited for a cross-over designed study. Each subject participated in two campaigns each comprising 3 days and 2 nights. Intervention started on the second campaign day and consisted of ma...
Source: Frontiers in Physiology - Category: Physiology Source Type: research

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