3D-bioprinted model mimics real human heart properties

Researchers from Israel have created a 3D-printed model that captures the immunological,...Read more on AuntMinnie.comRelated Reading: 3D printing reduces liver transplant costs, surgery time 3D printing helps separate rare case of conjoined twins 3D printing technique improves heart valve sizing 3D-printed aortas could work well for TAVR Flexible 3D-printed heart replicates size, texture
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news

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TUESDAY, Aug. 11, 2020 (American Heart Association News) -- Black people with severely malfunctioning heart valves are less likely than their white peers to receive lifesaving valve replacements, according to a new study. The study, published...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
Valvular heart disease has recently become an increasing public health concern due to the high prevalence of valve degeneration in aging populations. For patients with severely impacted aortic valves that require replacement, catheter-based bioprosthetic valve deployment offers a minimally invasive treatment option that eliminates many of the risks associated with...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Tags: Physical Sciences Source Type: research
Authors: Meddahi-Pelle A, Pavon-Djavid G, Chakfe N, Heim F Abstract Transcatheter Aortic Valve Implantation (TAVI) has become today a popular alternative technique to surgical valve replacement for critical patients. However, with only six years follow up on average, little is known about the long-term durability of transcatheter implanted biological tissue. Moreover, the high cost of tissue harvesting and chemical treatment procedures favor the development of alternative synthetic valve leaflet materials. In that context, thin, strong and flexible woven fibrous constructions could be considered as interesting cand...
Source: Biomedizinische Technik/Biomedical Engineering - Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research
TITUSVILLE, N.J. – (August 3, 2020) – The Janssen Pharmaceutical Companies of Johnson &Johnson today announced that the U.S. Food and Drug Administration (FDA) has approved the supplemental new drug application (sNDA) for SPRAVATO® (esketamine) CIII nasal spray, taken with an oral antidepressant, to treat depressive symptoms in adults with major depressive disorder (MDD) with acute suicidal ideation orbehavior.1 SPRAVATO® is the first and only approved medicine that has been shown to reduce depressive symptoms within 24 hours,1 providing a new option for significant symptom relief until a longer-ter...
Source: Johnson and Johnson - Category: Pharmaceuticals Tags: Innovation Source Type: news
Approximately 250,000 heart valve operations are performed annually worldwide. An intensive research and development effort has led to progressively more advanced heart valve prostheses. The Carpentier-Edwards...
Source: Journal of Cardiothoracic Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Research article Source Type: research
ConclusionsThere are opportunities to improve clinical outcomes of patients with high surgical risks and those undertaking heart valve procedures, as they tend to have poorer survival and higher risk in developing postsurgical complications.
Source: Journal of Cardiac Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: ORIGINAL ARTICLE Source Type: research
In this edition of Heart, Lung and Circulation, Amer and colleagues present the outcome of a metanalysis of 24 studies, with a total number of 5,073 patients, undergoing sutureless aortic valve replacement (SU-AVR) [1]. Mortality at one and twelve-month follow-up was 2.5% and 2.7%, respectively, with a low risk of thromboembolism (1.6%), and acceptable paravalvular leak (0.5%). These results corroborate the positive outcomes achieved at 30 days post-AVR [2,3], validating that the SU-AVR is safe and reduces operative time, especially in the setting of minimally invasive procedures.
Source: Heart, Lung and Circulation - Category: Cardiology Authors: Tags: Editorial Source Type: research
This study investigated the TTR in Hong Kong patients using both European and Japanese therapeutic ranges and patients' economic and clinical outcomes. Predictors of poor warfarin control and patient knowledge concerning warfarin therapy were assessed. METHODS: A 5-month observational study with retrospective and prospective components was conducted in the Prince of Wales Hospital. The study examined electronic patient records of patients who received warfarin for at least 1 year during the period from January 2010 to August 2015. Patient knowledge was assessed via phone interview using the Oral Anticoagulation Knowle...
Source: Hong Kong Med J - Category: General Medicine Authors: Tags: Hong Kong Med J Source Type: research
(Iowa State University) Iowa State and University of Texas engineers have developed high-fidelity computational models of replacement heart valves to examine the performance of biological tissues built into the valves. They found that thinner tissues can flap and flutter, which can damage the valves and even the blood that flows by.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
ConclusionsOne out of five patients were readmitted within 30 days after the TVR, associated with 6.1% mortality during rehospitalization, and very high need for skilled facility placement.
Source: Journal of Cardiac Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: ORIGINAL ARTICLE Source Type: research
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