3D-bioprinted model mimics real human heart properties

Researchers from Israel have created a 3D-printed model that captures the immunological,...Read more on AuntMinnie.comRelated Reading: 3D printing reduces liver transplant costs, surgery time 3D printing helps separate rare case of conjoined twins 3D printing technique improves heart valve sizing 3D-printed aortas could work well for TAVR Flexible 3D-printed heart replicates size, texture
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news

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(Medical University of South Carolina) Genetic mutations in heart valve cells of the developing fetus lead to mitral valve prolapse, report a global collaborative of researchers, including Medical University of South Carolina investigators, in today's Science Translational Medicine. These mutations or genetic variations cause defects in antenna-like cellular structures called primary cilia. This finding of a developmental cause for the disease highlights the importance of early intervention and may lead to the rethinking of treatment guidelines.
Source: EurekAlert! - Biology - Category: Biology Source Type: news
Authors: Liu J, Guan H, Zhou L, Cui Y, Cao W, Wang L Abstract AIM: To determine whether VKORC1 rs9923231, CYP2C9 rs1057910, CYP4F2 rs2108622 and ORM1 rs17650 genotypes contribute to warfarin therapy in patients during initiation and maintenance anticoagulation treatment after heart valve surgery. METHODS: 287 Chinese patients with warfarin treatment more than three month after heart valve replacement operations were enrolled. Blood was collected from each subject for DNA extraction and genotyping. Analyzing the relationship between genotypes and warfarin curative effect. RESULTS: Their mean age was 48.0 &pl...
Source: American Journal of Translational Research - Category: Research Tags: Am J Transl Res Source Type: research
- Late-breaking data for Abbott's investigational clip-based tricuspid heart valve repair system presented at EuroPCR
Source: Abbott.com - Category: Pharmaceuticals Source Type: news
The transcatheter approach increases treatment options for high-risk patients.
Source: National Institutes of Health (NIH) News Releases - Category: American Health Source Type: news
ez JL Abstract BACKGROUND: Left ventricular (LV) mechanics are impaired in patients with severe aortic stenosis (AS); however, transcatheter aortic valve implantation (TAVI) may positively affect LV mechanics. Assessed herein is the performance of the SAPIEN 3 transcatheter heart valve (THV) and the effect of TAVI on LV function recovery, as assessed by global longitudinal strain (GLS). METHODS: A subset of patients from the SOURCE 3 registry (n = 276) from 16 European centers received SAPIEN 3 balloon-expandable THV. Echocardiography was performed at baseline, post-procedure, and at 1 year, including assessm...
Source: Cardiology Journal - Category: Cardiology Authors: Tags: Cardiol J Source Type: research
Authors: Pozzoli A, Taramasso M, Haager P, Miura M, Gülmez G, Lin SI, Gavazzoni M, Rickli H, Maisano F Abstract The Portico™ transcatheter aortic valve implantation (TAVI) system (Abbott Vascular, Santa Clara, CA, USA) was specifically designed to reduce some of the limitations associated with first-generation TAVI devices. Most of the currently available clinical evidence was obtained from randomized studies that compared TAVI to aortic valve replacement using first-generation transcatheter heart valve devices. The aim of this review is to describe the characteristics of the repositionable and retrievab...
Source: Surgical Technology International - Category: Surgery Tags: Surg Technol Int Source Type: research
Abstract Right-sided infective endocarditis (IE) represents 5-10% of IE. It may occur in patients with electronic intracardiac device, central venous catheter or congenital heart disease, but the most frequent situation is intravenous drug use. Prosthetic valve IE is the most severe form of IE. The diagnosis is more challenging than that of native valve IE, as is treatment, both antibiotic treatment and surgical indications. The infection of an electronic intracardiac device is a severe disease. Both diagnostic and therapeutic strategies are difficult. PMID: 31109767 [PubMed - as supplied by publisher]
Source: Presse Medicale - Category: General Medicine Authors: Tags: Presse Med Source Type: research
Conclusion: The overall long-term clinical outcomes in these predominantly elderly patients undergoing AF ablation concomitantly with bioprosthetic valve replacement were satisfactory; however, AF recurrence was frequent. Older age, a history of prior cardiac surgery, and large LA size were associated with an increased risk of AF recurrence. PMID: 31089442 [PubMed]
Source: Korean Journal of Thoracic and Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Tags: Korean J Thorac Cardiovasc Surg Source Type: research
No abstract available
Source: Biomedical Safety and Standards - Category: Medical Devices Tags: RECALLS & FIELD CORRECTIONS—CLASS II Source Type: research
This study aimed to reduce this gap by evaluating three alternative levels at which lability could be incorporated into candidate polyurethane materials electroprocessed into a valve scaffold. Specifically, polyester and polycarbonate labile soft segment diols were reacted into thermoplastic elastomeric polyurethane ureas that formed scaffolds where: 1) a single polyurethane containing both of the two diols in the polymer backbone was synthesized and processed, 2) two polyurethanes were physically blended, one with exclusively polycarbonate and one with exclusively polyester diols, followed by processing of the blend, and ...
Source: Biomacromolecules - Category: Biochemistry Authors: Tags: Biomacromolecules Source Type: research
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