90 New Cases of Measles Reported in U.S. as Outbreak Continues Record Pace

This year ’ s outbreak is on course to be the worst since measles was eliminated as an endemic disease in 2000.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Measles Epidemics Centers for Disease Control and Prevention New York State Source Type: news

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This year ’ s outbreak is on course to be the worst since measles was eliminated as an endemic disease in 2000.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Measles Epidemics Centers for Disease Control and Prevention New York State Source Type: news
Abstract In the Netherlands there has been nationwide vaccination against the measles since 1977. However, a tight-knit community of a few hundred thousand orthodox protestants in the "Dutch Bible Belt" refuses the vaccine. Within this community of orthodox protestants there has been an outbreak of the measles with roughly 2500 reported cases about every twelve years. Each outbreak has lasted about a year. The community of orthodox protestants is too small to permanently keep the virus in circulation and have the infection be endemic. The dynamics in orthodox-protestant schools has been widely recognized...
Source: Biosystems - Category: Biotechnology Authors: Tags: Biosystems Source Type: research
Since the early 1990s, the Netherlands has experienced several large measles epidemics, in 1992-94, 1999-2000 and in 2013-14. These outbreaks mainly affected orthodox Protestants, a geographically clustered population with overall lower measles-mumps-rubella first dose (MMR-1) vaccination coverage (60%) than the rest of the country (>?95%). In the 2013-14 epidemic described here, which occurred between 27 May 2013 and 12 March 2014, 2,700 cases were reported. Several control measures were implemented including MMR vaccination for 6-14-month-olds and recommendations to reduce the risk in healthcare workers. The vast majo...
Source: Eurosurveillance - Category: Infectious Diseases Source Type: research
e; SJ Abstract Since the early 1990s, the Netherlands has experienced several large measles epidemics, in 1992-94, 1999-2000 and in 2013-14. These outbreaks mainly affected orthodox Protestants, a geographically clustered population with overall lower measles-mumps-rubella first dose (MMR-1) vaccination coverage (60%) than the rest of the country (> 95%). In the 2013-14 epidemic described here, which occurred between 27 May 2013 and 12 March 2014, 2,700 cases were reported. Several control measures were implemented including MMR vaccination for 6-14-month-olds and recommendations to reduce the risk in he...
Source: Euro Surveill - Category: Infectious Diseases Authors: Tags: Euro Surveill Source Type: research
Geneticists are exploring how disease introduced by European colonists shaped the evolution of indigenous peoples of the AmericasPrehistoric America was not a disease-free utopia.Tuberculosis, treponemal disease, Chagas disease, and many other pathogens were endemic to populations in different regions of the continent. But the“Columbian Exchange” beginning in 1492 introduced new pathogens to American populations, including smallpox, measles, influenza, and yellow fever. This introduction had devastating consequences for tribes. In some places, death from infectious disease resulted in thedepopulation of entire ...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Archaeology Science Genetics Biology Americas Epidemics Indigenous peoples Source Type: news
Amidst the fear surrounding Zika virus, remember that there are over 100,000 children born each year with birth defects caused by infection with rubella virus. The virus Rubella virus is a member of the Togaviridae family, which also includes chikungunya virus. The genome is a 9.7 kilobase, positive strand RNA enclosed in a capsid and surrounded by a membrane (illustrated; image from ViralZone). Transmission Humans are the only natural host and reservoir of rubella virus. The virus is transmitted from human to human by respiratory aerosols.  Upon entry into the upper respiratory...
Source: virology blog - Category: Virology Authors: Tags: Basic virology Information birth defects congenital rubella syndrome microcephaly mmr vaccine placenta viral virus viruses Zika zika virus Source Type: blogs
Discussion Except for the substantial initial transmission event that occurred within the Disney theme parks, the transmission of measles seen in the recent outbreak is relatively consistent with data from the past decade. In particular, amplification from 40 cases to 91 additional cases is consistent with subcritical transmission, with each case failing, on average, to replace itself, but playing out over several generations of transmission. Our primary estimate of the reproduction number, 0.69, is higher than the number obtained from US national data for 2001-2011 (0.52), but the difference is not statistically significa...
Source: PLOS Currents Outbreaks - Category: Epidemiology Authors: Source Type: research
Conclusions: The simulation results demonstrated the importance of vaccination coverage, clustering of immunity, and contact investigations in preventing uncontrolled measles outbreaks.
Source: BMC Public Health - Category: Consumer Health News Authors: Source Type: research
Conclusions: Prediction and early identification of spatial clusters of measles will be critical to achieving measles elimination. HIV infection may contribute to spatial clustering of measles cases in some epidemiological settings.
Source: BMC Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research
Abstract The World Health Organization (WHO) has adopted an elimination goal for measles and rubella, which is supposed to be met in the WHO European Region (EUR) by 2015. For verification of elimination, it is required that the genotyping data of detected measles viruses provide evidence for the interruption of endemic transmission. In order to record and assess the extent of endemic measles virus (MV) circulation in a part of the EUR, we analyzed transmission chains of the epidemiologically most relevant MV variants identified in Central and continental Western Europe (CCWE) from 2006 to 2013. Based on MV sequen...
Source: Virus Genes - Category: Genetics & Stem Cells Source Type: research
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