Gut-health expert reveals his 18 best tips to tackle irritable bowel syndrome
IBS is unpleasant to say the least and affects nearly half of us. But Dr Simon Smale, a consultant gastroenterologist at Manchester University, says we needn't suffer in silence.
Condition: Irritable Bowel Syndrome Characterized by Constipation Interventions: Drug: Botanical Tincture; Other: Placebo Sponsor: Stamford Hospital Not yet recruiting
This review explores possible etiologies for nonceliac gluten sensitivity, as well as the complex relationship between NCGS and irritable bowel syndrome.Current Opinion in Gastroenterology
Little is known about the link between pathophysiologic factors and symptoms of irritable bowel syndrome (IBS), or whether these factors have cumulative effects on patient-reported outcomes (PROs). We investigated whether pathophysiologic alterations associated with IBS have cumulative or independent effects on PROs.
CONCLUSIONS: Considering a conservative estimate of 2,736,700 Italian adults affected by the syndrome, the minimum costs due to IBS in Italy - likely underestimated - range from 6 to 8 billion euro per year. Given the substantial economic burden for patients, healthcare systems and society, IBS should be included among the priorities of the public health agenda. PMID: 31002149 [PubMed - in process]
ConclusionOral administration of XSLJZT (3.0 g) for 28 days lowered the mean diarrhea score in patients with IBS, indicating that the patients in the TG had greater diarrhea improvement than those in the CG. The present study used 10% XSLJZT as a comparator, and the different items of the Gastrointestinal System Rating Scale–IBS, IBS-QOL, and World Health Organization Quality of Life–Brief were scored separately. Therefore, the selection of an appropriate comparator or placebo and score assessment are crucial issues for future study.Graphical abstract
This article summarizes the current literature on the use of fecal calprotectin in clinical practice. PMID: 30999729 [PubMed - as supplied by publisher]
Functional gastrointestinal disorders are highly prevalent, cause significant suffering, and are costly to society. Pain is a central feature of 2 of the most common functional gastrointestinal disorders —irritable bowel syndrome and functional dyspepsia. Although these disorders have been well studied in adults, their etiology is poorly understood. We sought to identify early-life factors associated with development of abdominal pain in children (2–12 years old).
Publication date: Available online 17 April 2019Source: The Journal of Molecular DiagnosticsAuthor(s): Emily B. Hollister, Numan Oezguen, Bruno P. Chumpitazi, Ruth Ann Luna, Erica M. Weidler, Michelle Rubio-Gonzales, Mahmoud Dahdouli, Julia L. Cope, Toni-Ann Mistretta, Sabeen Raza, Ginger A. Metcalf, Donna M. Muzny, Richard A. Gibbs, Joseph F. Petrosino, Margaret Heitkemper, Tor C. Savidge, Robert J. Shulman, James VersalovicAccurate diagnosis and stratification of children with irritable bowel syndrome (IBS) remain challenging. Given the central role of recurrent abdominal pain in IBS, we evaluated the relationships of pe...
Most of us are familiar with post-traumatic stress disorder. PTSD (deservedly) gets a lot of attention, largely focused on soldiers returning from service. But trauma comes in many forms, and most people have experienced it in one form or another. In this episode, learn about the differences between PTSD and other forms of trauma, how to identify it, and what can be done about it. Subscribe to Our Show! And Remember to Review Us! About Our Guest Robert T. Muller, Ph.D., is the author of the psychotherapy book, “Trauma &the Struggle to Open Up: From Avoidance to Recovery &a...
In conclusion, our study might provide evidence that GQD treats diarrhea maybe involved in modulating gut microbiota and increasing SCFA levels. Introduction Diarrheal diseases cause approximately 1.7 billion new infections and 0.76 million deaths in children of under 5 years of age annually and are thus the second most common cause of mortality in young children in developing countries (Kotloff et al., 2012, 2013). Outbreaks of such diseases are usually related to infection by common causative agents, mainly rotavirus, Salmonella enterica, and diarrheagenic Escherichia coli (Hodges and Gill, 2010; Kolenda et al., ...