The Functional Head Impulse Test to Assess Oscillopsia in Bilateral Vestibulopathy

This study compared the fHIT with the Dynamic Visual Acuity assessed on a treadmill (DVAtreadmill) and Oscillopsia Severity Questionnaire (OSQ) in the context of objectifying the experience of oscillopsia in patients with BV. Methods: Inclusion criteria comprised: (1) summated slow phase velocity of nystagmus of
Source: Frontiers in Neurology - Category: Neurology Source Type: research

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Source: BMJ Comments - Category: General Medicine Source Type: forums
ConclusionsThe CAUTI incidence is reduced through QCC, providing a useful reference for the prevention of CAUTI and the development of medical quality improvement activities.
Source: American Journal of Infection Control - Category: Infectious Diseases Source Type: research
AbstractWarfarin is a narrow therapeutic index anticoagulant drug, and several generic formulations have been approved worldwide. However, there has been no report evaluating the bioequivalence of warfarin sodium according to US Food and Drug Administration draft guidance. We designed a 2 ‐sequence and 4‐period crossover study to compare the pharmacokinetic profile and assess bioequivalence between the test warfarin sodium tablet and reference product Coumadin (2.5 mg) in 56 healthy Chinese subjects under fasting and fed conditions. The plasma concentration of warfarin was analy zed by a validated liquid chromatog...
Source: Clinical Pharmacology in Drug Development - Category: Drugs & Pharmacology Authors: Tags: Original Manuscript Source Type: research
Abstract Intergenic region of begomovirus genome is vital to virus replication and viral gene transcription in plants. Previous studies have reported that Tomato yellow leaf curl China virus (TYLCCNV), a begomovirus, is able to accumulate and transcribe in its whitefly vector. However, the viral and host components that participate in begomovirus transcription in whiteflies are hitherto unknown. Using a yeast one-hybrid system, we identified>50 whitefly proteins that interacted with TYLCCNV intergenic region. Dual luciferase analysis revealed that one of the identified proteins, the hairy and enhancer of split ...
Source: Virology - Category: Virology Authors: Tags: Virology Source Type: research
Conclusion: OCTA can detect alterations in choriocapillaris flow. Longitudinal follow-up demonstrates a centripetal restoration of choriocapillaris flow in response to immunosuppressive therapy. OCTA may be a useful adjunct for monitoring and evaluating treatment of PIC. PMID: 32058825 [PubMed - as supplied by publisher]
Source: Ocular Immunology and Inflammation - Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research
Publication date: Available online 16 February 2020Source: Journal of Psychiatric ResearchAuthor(s): Carisha S. Thesing, Mariska Bot, Yuri Milaneschi, Erik J. Giltay, Brenda W.J.H. PenninxAbstractBackgroundTemporality of the association of low omega-3 polyunsaturated fatty acid (n-3 PUFA) plasma levels with depression remains questionable. To determine the underlying nature of these associations, this study examined the bidirectional longitudinal associations of n-3 PUFA plasma levels with (presence, onset and course of) depressive disorders and symptoms.MethodsBaseline (n = 2912, 28.6% with current depressive disorder...
Source: Journal of Psychiatric Research - Category: Psychiatry Source Type: research
Publication date: Available online 15 February 2020Source: Neuroscience &Biobehavioral ReviewsAuthor(s): Pu Hu, Anne-Marie van Dam, Yu Wang, Paul J. Lucassen, Jiang-Ning ZhouAbstractThe retinoid family members, including vitamin A and derivatives like 13-cis-retinoic acid (ITT) and all-trans retinoic acid (ATRA), are essential for normal functioning of the developing and adult brain. When vitamin A intake is excessive, however, or after ITT treatment, increased risks have been reported for depression and suicidal ideation.Here, we review pre-clinical and clinical evidence supporting association between retinoids and de...
Source: Neuroscience and Biobehavioral Reviews - Category: Neuroscience Source Type: research
DiscussionSetting optimized thyrotropin cutoffs for reflex testing of free thyroxine would reduce the need for this test. Clinical laboratories need to offer not only true results, but also become the cornerstone in the optimization of resources.
Source: Clinica Chimica Acta - Category: Laboratory Medicine Source Type: research
DiscussionDystrophin deficiency likely disrupts Octn2 expression decreasing muscle carnitine uptake thus contributing to membranotoxic long-chain acyl-CoAs with sarcolemmal and organellar membrane oxidative injury providing a treatment rationale for early L-carnitine in DMD.
Source: Clinica Chimica Acta - Category: Laboratory Medicine Source Type: research
In this study, the Cyprinus carpio intoxication model was used to compare the differences in intoxication effect of alcoholic beverages and to assess the impacts of huangjiu components on intoxication for the first time. Exposure to huangjiu led to the most rapid physical imbalance of C. carpio, followed by red wine and Western liquor. Higher alcohols, biogenic amines and aldehydes could cause physical imbalance of fish by themselves, and synergistic effects were observed when combined with ethanol. 2-Phenylethanoland and isopentanol had the greatest positive effect on huangjiu intoxication, followed by histamine and phene...
Source: Food Chemistry - Category: Food Science Source Type: research
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