Effect of STN DBS on vesicular monoamine transporter 2 and glucose metabolism in Parkinson's disease

The objective of the present study was to elucidate the effects of STN DBS in PD on the dopamine system and neural circuitry. High-resolution positron emission tomography imaging of the vesicular monoamine transporter (VMAT2) and cerebral glucose metabolism were performed prior to DBS surgery and after 4 –6 months of STN stimulation.

Source: Parkinsonism and Related Disorders - April 14, 2019 Category: Neurology Authors: Gwenn S. Smith, Kelly A. Mills, Greg M. Pontone, W. Stanley Anderson, Kate M. Perepezko, James Brasic, Hiroto Kuwabara, Yun Zhou, Jason Brandt, Christopher R. Butson, Daniel P. Holt, William B. Mathews, Robert F. Dannals, Dean F. Wong, Zoltan Mari Source Type: research