Eczema: The popular spice which may help to reduce itchy eczema symptoms

ECZEMA is typically treated with medicated creams and ointments, but more and more people are turning to natural remedies to soothe the itchy symptoms. One spice which may help to soothe eczema symptoms is turmeric.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news

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Ion channels have emerged as potential mediators of chronic skin disease. Here, we explored the consequences of genetically encoded induction of the cell volume-regulating Ca2+-activated KCa3.1 channel (Kcnn4) for murine epidermal homeostasis. 800-fold channel overexpression in keratinocytes of doxycycline-treated KCa3.1+ mice produced strong KCa3.1-functions, epidermal spongiosis, progressive epidermal hyperplasia, hyperkeratosis, itch and ulcers, and high morbidity within two weeks. We found significant induction of pro-proliferative and pro-inflammatory cytokines, IL- β1 (60-fold over basal levels), IL-23 (34-fold)...
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Epidermal Structure and Barrier Function Source Type: research
Itch is the most bothersome symptom of atopic dermatitis (AD). Improvement in itch is an important marker of treatment benefit in AD patients. In dupilumab (DPL) phase 3, double-blind, placebo (PBO)-controlled trials, we assessed intensity and frequency of itch using Peak Pruritus Numerical Rating Scale (PP-NRS), Scoring AD (SCORAD) itch Visual Analog Scale (VAS), and Patient-Oriented Eczema Measure (POEM) itch item, in adults with moderate-to-severe AD who received DPL 300mg every 2 weeks (q2w) or PBO monotherapy (pooled SOLO 1&2: NCT02277743, NCT02277769; 16-week [Wk]), or combined with topical corticosteroids (CHRONOS: ...
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Interventional Studies, Clinical and Patient Outcomes Research Source Type: research
A Phase 1b, multi-center, randomized, double-blind, vehicle-controlled study was conducted in 48 adult patients with mild-to-moderate atopic dermatitis (AD). 17, and 14 patients received SB414 2% cream, SB414 6% cream and vehicle, respectively, twice daily for 2 weeks. SB414 showed trends suggestive of efficacy based on the change in eczema area severity index (EASI), itch numerical rating score (NRS) and target lesion severity score. Both SB414 2% and 6% were well tolerated, but 2% had a more favorable local tolerability profile with no quantifiable systemic exposure.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Interventional Studies, Clinical and Patient Outcomes Research Source Type: research
Quality of life (QOL) assessments are not standardized in atopic dermatitis (AD). We sought to determine the validity of Short-Form 12 (SF-12), a generic QOL assessment, in AD and compare its measurement properties with Dermatology Life Quality Index (DLQI). A cross-sectional, population-based study of 3495 adults was performed, including 602 that met a modified UK Working Party Criteria for AD. SF-12 mental component score (MCS) and SF-6D had a strong correlation with each other, and moderate inverse correlations with Patient-Oriented Eczema Measure, Patient Oriented-Scoring AD (PO-SCORAD), PO-SCORAD –itch, PO-SCORA...
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Original Article Source Type: research
ECZEMA can leave the skin feeling itchy, dry and sore, and sometimes flare-ups can be hard to control. As more and more people are looking at natural remedies to treat symptoms, some experts recommend a particular sweet food spread.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
ECZEMA is a condiiton that causes skin to become itchy, dry and inflammed, and for one baby the condition stopped him from being able to crawl. He finally found relief for the skin condition in a high street cream.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
ECZEMA could be treated by using creams, moisturisers or emollients. But how could you get rid of the dry skin condition at home? These are the best natural moisturisers to relieve the itchy and sore signs of eczema.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Abstract BACKGROUND: Structured patient-reported outcomes of AD severity are not standardized in clinical practice. We sought to determine the construct validity, internal consistency, cross-cultural validity, floor or ceiling effects of multiple AD severity assessments. METHODS: A cross-sectional, population-based study of 2893 adults, including 602 adults that met a modified UK Diagnostic Criteria for AD. AD severity was assessed using self-reported global AD severity, Patient-Oriented Eczema Measure (POEM), Patient-Oriented Scoring AD (PO-SCORAD) and its objective and subjective components, and numerical r...
Source: The British Journal of Dermatology - Category: Dermatology Authors: Tags: Br J Dermatol Source Type: research
ECZEMA could be treated by using creams, moisturisers or emollients. But you could also get rid of the dry skin condition at home by using this natural essential oil as a moisturiser. It may help to relieve the itchy and sore signs of eczema.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
In this study we used HPLC and LC/MS analysis, combined with a BATMAN-TCM platform, for detailed HPLC fingerprint analysis and network pharmacology of QP, and investigated the anti-inflammatory and antipruritic activities of QP on ACD induced by squaric acid dibutylester (SADBE) in mice. The BATMAN-TCM analysis provided information of effector molecules of the main ingredients of QP, and possible chronic dermatitis-associated molecules and cell signaling pathways by QP. In ACD mice, QP treatment suppressed the scratching behavior induced by SADBE in a dose-dependent manner and inhibited the production of Th1/2 cytokines in...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
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