Meet the B.C. man who has reversed more than 190 overdoses

Dwayne Martin is full of survival stories.
Source: CBC | Health - Category: Consumer Health News Tags: News/Canada/British Columbia Source Type: news

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Nurses in New York are using geospatial mapping of opioid overdoses to inform clinical practice at a local clinic level in “real time”, according to US researchers.
Source: Nursing Times - Category: Nursing Source Type: news
Veronica Chico1,2, Maria Elizabhet Salvador-Mira1,2, Ivan Nombela1,2, Sara Puente-Marin1,2, Sergio Ciordia3, María Carmen Mena3, Luis Perez1,2, Julio Coll4, Fanny Guzman5, Jose Antonio Encinar1,2, Luis Mercado5 and Maria del Mar Ortega-Villaizan1,2* 1Departamento de Bioquímica y Biología Molecular, Instituto de Biología Molecular y Celular (IBMC), Universidad Miguel Hernández (UMH), Elche, Spain 2Departamento de Bioquímica y Biología Molecular, Instituto de Investigación, Desarrollo e Innovación en Biotecnologîa Sanitaria de Elche (IDiBE), Univers...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
This study was supported by grants from Alpaca Research Foundation 2009–2011, Morris Animal Foundation D09LA-004, and Willamette Valley Llama Association. Conflict of Interest Statement The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Footnotes ^ References Alvarenga, M. A., Landim-Alvarenga, F. C., Moreira, R. M., and Cesarino, M. M. (2000). Acrosomal ultrastructure of stallion spermatozoa cryopreserved with ethylene glycol using two packaging systems. E...
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
By ETIENNE DEFFARGES According the 2019 Bloomberg Healthiest Country Index, the U.S. ranks 35th out of 169 countries. Even though we are the 11th wealthiest country in the world, we are behind pretty much all developed economies in terms of health. In the Americas, not just Canada (16th) but also Cuba (30th), Chile and Costa Rica (tied for 33rd) rank ahead of us in this Bloomberg study. To answer this layered question, we need to look at the top ranked countries in the Bloomberg Index: From first to 12th, they are Spain; Italy; Iceland; Japan; Switzerland; Sweden; Australia; Singapore; Norway; Israel; Luxe...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: Economics Health disparities Health Policy American healthcare Etienne Deffarges Mediterranean Diet Opioids world health Source Type: blogs
Abstract Post-release opioid-related overdose mortality is the leading cause of death among people released from jails or prisons (PRJP). Informed by the proximate determinants framework, this paper presents the Post-Release Opioid-Related Overdose Risk Model. It explores the underlying, intermediate, proximate and biological determinants which contribute to risk of post-release opioid-related overdose mortality. PRJP share the underlying exposure of incarceration and the increased prevalence of several moderators (chronic pain, HIV infection, trauma, race, and suicidality) of the risk of opioid-related overdose. ...
Source: Addiction Science and Clinical Practice - Category: Addiction Authors: Tags: Addict Sci Clin Pract Source Type: research
Publication date: 13–19 April 2019Source: The Lancet, Volume 393, Issue 10180Author(s): Paul Glare, Karin R Aubrey, Paul S MylesSummaryOver the past decade there has been an increasing reliance on strong opioids to treat acute and chronic pain, which has been associated with a rising epidemic of prescription opioid misuse, abuse, and overdose-related deaths. Deaths from prescription opioids have more than quadrupled in the USA since 1999, and this pattern is now occurring globally. Inappropriate opioid prescribing after surgery, particularly after discharge, is a major cause of this problem. Chronic postsurgical pain...
Source: The Lancet - Category: General Medicine Source Type: research
Publication date: Available online 12 April 2019Source: Chemico-Biological InteractionsAuthor(s): Xiabin Chen, Jing Deng, Xirong Zheng, Jinling Zhang, Ziyuan Zhou, Huimei Wei, Chang-Guo Zhan, Fang ZhengAbstractHuman butyrylcholinesterase (BChE) is known as a safe and effective protein for detoxification of organophosphorus (OP) nerve agents. Its rationally designed mutants with considerably improved catalytic activity against cocaine, known as cocaine hydrolases (CocHs), are recognized as the most promising drug candidates for the treatment of cocaine abuse. However, it is a grand challenge to efficiently produce active re...
Source: Chemico Biological Interactions - Category: Biochemistry Source Type: research
CONCLUSIONS: Buprenorphine and BNX continue to be injected, albeit in small numbers. This is the first study to report on injection and overdose risk using direct observation, and has confirmed the lower overdose risk. MSIC clients who inject buprenorphine and BNX tend to be marginalized and may benefit from targeted harm reduction measures. PMID: 30973286 [PubMed - as supplied by publisher]
Source: Substance Use and Misuse - Category: Addiction Tags: Subst Use Misuse Source Type: research
We report such a case in an adolescent male.
Source: Journal of the Neurological Sciences - Category: Neurology Authors: Tags: Letter to the Editor Source Type: research
A new kind of overdose is showing up among Vancouver drug users and it’s scaring front-line workers who are trying to save fentanyl users who are using substances adulterated with bizarre and dangerous fillers.
Source: CBC | Health - Category: Consumer Health News Tags: News/Canada/British Columbia Source Type: news
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