Clinical utility of genomic analysis in adults with idiopathic liver disease

Chronic liver disease (CLD) is a significant health problem affecting more than 4 million people in the United States and leading to over 40,000 deaths annually.1 CLD is often undiagnosed for many years unless there is awareness of subtle clinical signs, behavioral risk factors and/or investigation of abnormal liver function tests. In many patients, by the time overt manifestations of CLD emerge, liver injury has advanced to result in portal hypertension or hepatic decompensation. The taxonomy of CLD in clinical practice is based broadly on categories of etiology such as exposure to toxins, viral infections, cholestatic, autoimmune, metabolic and select genetic disorders.
Source: Journal of Hepatology - Category: Gastroenterology Authors: Tags: Research Article Source Type: research