Pancreatic development: one cell at a (pseudo)time

Gaining a comprehensive understanding of the principles guiding lineage differentiation during organogenesis is a challenge. In this issue, Yu et al (2019) tackle this venture by taking advantage of single-cell transcriptomic analyses and multiple mouse genetic tools. Their work provides new insights into pancreatic endocrine and exocrine cell differentiation landscapes and identifies new pathways regulating pancreatic lineage allocation in vivo.

Source: EMBO Journal - April 14, 2019 Category: Molecular Biology Authors: Liu, Z., Sneddon, J. B. Tags: Development & Differentiation, Systems & Computational Biology News [amp ] Views Source Type: research